| Literature DB >> 22402950 |
Y Feng1, S Busch, N Gretz, S Hoffmann, H-P Hammes.
Abstract
Diabetic retinopathy shares important features with neurodegenerative retinal diseases, including loss of ganglion cells and retinal thinning. The impact on vasoregression and subsequent ischemia-driven changes such as macular edema and proliferative retinopathy are not established. Studies using adult neurodegenerative animal models such as the transgenic TGR(CMV-PKD2(1/703)HA) rat imply early activation of the innate immunity system and the complement system as well as microglia playing a role in the damage of the retinal neurovascular unit. © J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York.Entities:
Mesh：
Year: 2012 PMID： 22402950 DOI： 10.1055/s-0032-1304571
Source DB: PubMed Journal: Exp Clin Endocrinol Diabetes ISSN： 0947-7349 Impact factor: 2.949