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Literature DB >> 22401799

Tissue factor controversies.

Kenneth G Mann¹, Jolanta Krudysz-Amblo, Saulius Butenas.

Abstract

Tissue factor plays a primary role in both hemorrhage control and thrombosis depending upon whether its presentation is extravascular or intravascular. The molecular architecture and function of the tissue factor molecule and its role in the activations of factor IX and factor X have been elegantly elucidated but controversies prevail with respect to distinctions between tissue factor sources and tissue factor "activity." This presentation will review data on the architecture and functions of the tissue factor-factor VIIa complex and discuss the elements of the controversies associated with tissue factor presentation in both normal and pathologic milieu.

Entities: CellLine Chemical Disease Gene Species

Mesh：

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Year: 2012 PMID： 22401799 PMCID： PMC3395078 DOI： 10.1016/j.thromres.2012.02.018

Source DB: PubMed Journal: Thromb Res ISSN： 0049-3848 Impact factor: 3.944

32 in total

1. Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.

Authors: B Osterud; S I Rapaport
Journal: Proc Natl Acad Sci U S A Date: 1977-12 Impact factor: 11.205

2. Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade.

Authors: N Mackman; J H Morrissey; B Fowler; T S Edgington
Journal: Biochemistry Date: 1989-02-21 Impact factor: 3.162

2. Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase.

Authors: Florian Langer; Brigitte Spath; Cornelia Fischer; Moritz Stolz; Francis A Ayuk; Nicolaus Kröger; Carsten Bokemeyer; Wolfram Ruf
Journal: Blood Date: 2013-01-11 Impact factor: 22.113

2 in total

Tissue factor controversies.

1. Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.

2. Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade.

3. Successful use of recombinant factor VIIa in patient with severe haemophilia A during synovectomy.

4. Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA.

5. Post-translational modifications of recombinant human tissue factor.

Review 6. Regulation of the procoagulant response to arterial injury.

7. Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine.

8. Purification and characterization of bovine tissue factor.

9. Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein.

10. Human platelets synthesize and express functional tissue factor.

1. Methyl isocyanate inhalation induces tissue factor-dependent activation of coagulation in rats.

2. Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase.