Literature DB >> 22400095

Acute lead poisoning in an infant.

M Madhusudhanan, S B Lall.   

Abstract

A case of acute lead poisoning in an infant without overt clinical manifestations of encephalopathy is reported for the first time in Oman. The case was diagnosed at Rustaq Hospital on the basis of (i) history by the mother of giving the child a traditional remedy for treating constipation (ii) X-ray of abdomen showing radio-opaque speckles and (iii) detection of high blood lead levels (83.3 µg/dL) at the toxicology laboratory of the poison control centre. The source of lead was confirmed by high content of inorganic lead (20.2%) found in the sample of the traditional remedy (bint al dahab). The blood lead levels significantly decreased, after the intravenous calcium edetate (EDTA) therapy was given to the baby. The case highlights that early detection and treatment of acute lead poisoning in children can prevent morbidity and sequelae associated with encephalopathy. It also indicated the need for awareness and prevention programme for parents on this issue.

Entities:  

Year:  2007        PMID: 22400095      PMCID: PMC3294150     

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  12 in total

1.  Cognitive deficits associated with blood lead concentrations <10 microg/dL in US children and adolescents.

Authors:  B P Lanphear; K Dietrich; P Auinger; C Cox
Journal:  Public Health Rep       Date:  2000 Nov-Dec       Impact factor: 2.792

2.  Lead poisoning in infancy--unusual causes in the U.A.E.

Authors:  H Rahman; A Al Khayat; N Menon
Journal:  Ann Trop Paediatr       Date:  1986-09

3.  Lead intoxication in infancy.

Authors:  M W Shannon; J W Graef
Journal:  Pediatrics       Date:  1992-01       Impact factor: 7.124

4.  Low-level lead exposure and the IQ of children. A meta-analysis of modern studies.

Authors:  H L Needleman; C A Gatsonis
Journal:  JAMA       Date:  1990-02-02       Impact factor: 56.272

5.  Lead poisoning associated with use of traditional ethnic remedies--California, 1991-1992.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1993-07-16       Impact factor: 17.586

6.  Fatal pediatric poisoning from leaded paint--Wisconsin, 1990.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1991-03-29       Impact factor: 17.586

7.  Aetiology of acute lead encephalopathy in Omani infants.

Authors:  D A Woolf
Journal:  J Trop Pediatr       Date:  1990-12       Impact factor: 1.165

8.  The developmental consequences of low to moderate prenatal and postnatal lead exposure: intellectual attainment in the Cincinnati Lead Study Cohort following school entry.

Authors:  K N Dietrich; O G Berger; P A Succop; P B Hammond; R L Bornschein
Journal:  Neurotoxicol Teratol       Date:  1993 Jan-Feb       Impact factor: 3.763

9.  Lead encephalopathy in infants in Kuwait. A study of 20 infants with particular reference to clinical presentation and source of lead poisoning.

Authors:  A Shaltout; S A Yaish; N Fernando
Journal:  Ann Trop Paediatr       Date:  1981-12

10.  Pregnancy increases mobilization of lead from maternal skeleton.

Authors:  B L Gulson; C W Jameson; K R Mahaffey; K J Mizon; M J Korsch; G Vimpani
Journal:  J Lab Clin Med       Date:  1997-07
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  2 in total

Review 1.  Lead poisoning: acute exposure of the heart to lead ions promotes changes in cardiac function and Cav1.2 ion channels.

Authors:  Gonzalo Ferreira de Mattos; Carlos Costa; Florencia Savio; M Alonso; G L Nicolson
Journal:  Biophys Rev       Date:  2017-08-23

Review 2.  Rationale for the Successful Management of EDTA Chelation Therapy in Human Burden by Toxic Metals.

Authors:  Maria Elena Ferrero
Journal:  Biomed Res Int       Date:  2016-11-08       Impact factor: 3.411

  2 in total

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