Literature DB >> 22400084

Transjugular intrahepatic porto-systemic shunt in the elderly: Palliation for complications of portal hypertension.

Mubin I Syed1, Hetal Karsan, Hector Ferral, Azim Shaikh, Uzma Waheed, Talal Akhter, Alan Gabbard, Kamal Morar, Robert Tyrrell.   

Abstract

AIM: To present a dedicated series of transjugular intrahepatic porto-systemic shunts (TIPS) in the elderly since data is sparse on this population group.
METHODS: A retrospective review was performed of patients at least 65 years of age who underwent TIPS at our institutions between 1997 and 2010. Twenty-five patients were referred for TIPS. We deemed that 2 patients were not considered appropriate candidates due to their markedly advanced liver disease. Of the 23 patients suitable for TIPS, the indications for TIPS placement was portal hypertension complicated by refractory ascites alone (n = 9), hepatic hydrothorax alone (n = 2), refractory ascites and hydrothorax (n = 1), gastrointestinal bleeding alone (n = 8), gastrointestinal bleeding and ascites (n = 3).
RESULTS: Of these 23 attempted TIPS procedure patients, 21 patients had technically successful TIPS procedures. A total of 29 out of 32 TIPS procedures including revisions were successful in 21 patients with a mean age of 72.1 years (range 65-82 years). Three of the procedures were unsuccessful attempts at TIPS and 8 procedures were successful revisions of our existing TIPS. Sixteen of 21 patients who underwent successful TIPS (excluding 5 patients lost to follow-up) were followed for a mean of 14.7 mo. Ascites and/or hydrothorax was controlled following technically successful procedures in 12 of 13 patients. Bleeding was controlled following technically successful procedures in 10 out of 11 patients.
CONCLUSION: We have demonstrated that TIPS is an effective procedure to control refractory complications of portal hypertension in elderly patients.

Entities:  

Keywords:  Ascites; Cirrhosis; Elderly; Portal hypertension; Transjugular intrahepatic porto-systemic shunt

Year:  2012        PMID: 22400084      PMCID: PMC3295850          DOI: 10.4254/wjh.v4.i2.35

Source DB:  PubMed          Journal:  World J Hepatol


  25 in total

Review 1.  The role of transjugular intrahepatic portosystemic shunt (TIPS) in the management of portal hypertension.

Authors:  Luis Colombato
Journal:  J Clin Gastroenterol       Date:  2007 Nov-Dec       Impact factor: 3.062

2.  [Use of transjugular intrahepatic portosystemic shunt (TIPS) in an 84 year-old patient during acute variceal bleeding].

Authors:  A R Grinberg; F de la Serna; M Silva; J D Finkielman; E Magariños; H M Festa; G A Lorenzino; C A Cazenave
Journal:  Medicina (B Aires)       Date:  1998       Impact factor: 0.653

3.  Use of CT-guided marking of the portal vein in creation of 150 transjugular intrahepatic portosystemic shunts.

Authors:  A B Fontaine; A Verschyl; E Hoffer; J Borsa; M Dowd
Journal:  J Vasc Interv Radiol       Date:  1997 Nov-Dec       Impact factor: 3.464

4.  Early use of TIPS in patients with cirrhosis and variceal bleeding.

Authors:  Juan Carlos García-Pagán; Karel Caca; Christophe Bureau; Wim Laleman; Beate Appenrodt; Angelo Luca; Juan G Abraldes; Frederik Nevens; Jean Pierre Vinel; Joachim Mössner; Jaime Bosch
Journal:  N Engl J Med       Date:  2010-06-24       Impact factor: 91.245

Review 5.  Selection criteria for patients undergoing transjugular intrahepatic portosystemic shunt procedures: current status.

Authors:  Hector Ferral; Nilesh H Patel
Journal:  J Vasc Interv Radiol       Date:  2005-04       Impact factor: 3.464

6.  TIPS for the treatment of refractory ascites, hepatorenal syndrome and hepatic hydrothorax: a critical update.

Authors:  Martin Rössle; Alexander L Gerbes
Journal:  Gut       Date:  2010-07       Impact factor: 23.059

7.  Treatment of refractory hepatic hydrothorax with transjugular intrahepatic portosystemic shunt: long-term results in 40 patients.

Authors:  V Siegerstetter; P Deibert; A Ochs; M Olschewski; H E Blum; M Rössle
Journal:  Eur J Gastroenterol Hepatol       Date:  2001-05       Impact factor: 2.566

Review 8.  Predictors of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in cirrhotic patients: a systematic review.

Authors:  Ming Bai; Xingshun Qi; Zhiping Yang; Zhanxin Yin; Yongzhan Nie; Shanshan Yuan; Kaichun Wu; Guohong Han; Daiming Fan
Journal:  J Gastroenterol Hepatol       Date:  2011-06       Impact factor: 4.029

9.  The use of a polytetrafluoroethylene-covered stent graft for transjugular intrahepatic portosystemic shunt (TIPS): Long-term follow-up of 100 patients.

Authors:  M Rössle; V Siegerstetter; W Euringer; M Olschewski; J Kromeier; K Kurz; M Langer
Journal:  Acta Radiol       Date:  2006-09       Impact factor: 1.990

10.  Transjugular intrahepatic portal systemic shunt for the management of symptomatic cirrhotic hydrothorax.

Authors:  R M Strauss; L G Martin; S L Kaufman; T D Boyer
Journal:  Am J Gastroenterol       Date:  1994-09       Impact factor: 10.864

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  4 in total

Review 1.  Cirrhotic patients and older people.

Authors:  Paul Carrier; Marilyne Debette-Gratien; Jérémie Jacques; Véronique Loustaud-Ratti
Journal:  World J Hepatol       Date:  2019-09-27

2.  Outcomes After Transjugular Intrahepatic Portosystemic Shunt in Cirrhotic Patients 70 Years and Older.

Authors:  Natasha Adlakha; Mark W Russo
Journal:  J Clin Med       Date:  2020-01-31       Impact factor: 4.241

3.  Transjugular intrahepatic portosystemic shunt using the FLUENCY expanded polytetrafluoroethylene-covered stent.

Authors:  Qinghua Wu; Jianwei Jiang; Yujie He; Tianpeng Jiang; Shi Zhou
Journal:  Exp Ther Med       Date:  2012-10-30       Impact factor: 2.447

4.  Efficacy of nonsurgical tigecycline pleurodesis for the management of hepatic hydrothorax in patients with liver cirrhosis.

Authors:  Nevin Yilmaz; Arife Zeybek; Benjamin Tharian; Ugur Eser Yilmaz
Journal:  Surg Case Rep       Date:  2015-08-12
  4 in total

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