| Literature DB >> 22399606 |
Juliana Noguti1, Carolina Foot Gomes DE Moura, Thais Ayako Hossaka, Marcello Franco, Celina Tijuko Fujiyama Oshima, Rogerio Aparecido Dedivitis, Daniel Araki Ribeiro.
Abstract
Oral cancer is a common neoplasm worldwide. The incidence and mortality have also increased in recent decades. It is characterized by poor prognosis and a low survival rate despite sophisticated surgical and radiotherapeutic modalities. The WNTs comprise a large family of highly conserved growth factors associated with a number of functions. In this review, we focus largely on the canonical pathway, revealing the recent findings, in oral cancer research, thereby raising our understanding of the mechanisms of this crucial signaling in several cellular activities.Entities:
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Year: 2012 PMID： 22399606
Source DB: PubMed Journal: Anticancer Res ISSN： 0250-7005 Impact factor: 2.480