Literature DB >> 22399263

Impersonalized medicine.

Heidi Scrable1.   

Abstract

Research reported in this issue of Science Translational Medicine illustrates the benefits of short-term food withdrawal (fasting) in the treatment of cancer. Fasting exploited fundamental differences in the way tumor cells and normal cells respond to stress, simultaneously strengthening normal cell function and weakening tumor cell survival in the presence of toxic doses of chemotherapeutic drugs.

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Year:  2012        PMID: 22399263     DOI: 10.1126/scitranslmed.3003738

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN: 1946-6234            Impact factor:   17.956


  1 in total

1.  A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitation.

Authors:  Jixiu Shan; Mukundh N Balasubramanian; William Donelan; Lingchen Fu; Jaclyn Hayner; Maria-Cecilia Lopez; Henry V Baker; Michael S Kilberg
Journal:  J Biol Chem       Date:  2014-07-15       Impact factor: 5.157

  1 in total

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