Literature DB >> 22398601

Hedgehog hopes lifted by approval... and stung by failure.

Malorye Allison.   

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Year:  2012        PMID： 22398601     DOI： 10.1038/nbt0312-203

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  9 in total

1.  Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer.

Authors:  Mohammad Aslam Khan; Sanjeev Kumar Srivastava; Haseeb Zubair; Girijesh Kumar Patel; Sumit Arora; Moh'd Khushman; James Elliot Carter; Gregory Stephen Gorman; Seema Singh; Ajay Pratap Singh
Journal:  J Biol Chem       Date:  2020-05-01       Impact factor: 5.157

2.  Fresh from the biotech pipeline--2012.

Authors:  Randy Osborne
Journal:  Nat Biotechnol       Date:  2013-02       Impact factor: 54.908

3.  Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk.

Authors:  Courey Averett; Arun Bhardwaj; Sumit Arora; Sanjeev K Srivastava; Mohammad Aslam Khan; Aamir Ahmad; Seema Singh; James E Carter; Moh'd Khushman; Ajay P Singh
Journal:  Carcinogenesis       Date:  2016-11-01       Impact factor: 4.944

4.  Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation.

Authors:  Yu Wang; Anthony C Arvanites; Lance Davidow; Joel Blanchard; Kelvin Lam; Jin Woo Yoo; Shannon Coy; Lee L Rubin; Andrew P McMahon
Journal:  ACS Chem Biol       Date:  2012-05-03       Impact factor: 5.100

5.  Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity.

Authors:  Yu Wang; Lance Davidow; Anthony C Arvanites; Joel Blanchard; Kelvin Lam; Ke Xu; Vatsal Oza; Jin Woo Yoo; Jessica M Y Ng; Tom Curran; Lee L Rubin; Andrew P McMahon
Journal:  Chem Biol       Date:  2012-08-24

6.  Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications.

Authors:  Mohammad Aslam Khan; Sanjeev K Srivastava; Arun Bhardwaj; Seema Singh; Sumit Arora; Haseeb Zubair; James E Carter; Ajay P Singh
Journal:  Oncotarget       Date:  2015-11-17

Review 7.  Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward.

Authors:  Mohammad Aslam Aslam Khan; Shafquat Azim; Haseeb Zubair; Arun Bhardwaj; Girijesh Kumar Patel; Moh'd Khushman; Seema Singh; Ajay Pratap Singh
Journal:  Int J Mol Sci       Date:  2017-04-06       Impact factor: 5.923

8.  Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK.

Authors:  Girijesh Kumar Patel; Mohammad Aslam Khan; Arun Bhardwaj; Sanjeev K Srivastava; Haseeb Zubair; Mary C Patton; Seema Singh; Moh'd Khushman; Ajay P Singh
Journal:  Br J Cancer       Date:  2017-02-02       Impact factor: 7.640

9.  The dawn of hedgehog inhibitors: Vismodegib.

Authors:  Selvarajan Sandhiya; George Melvin; Srinivasamurthy Suresh Kumar; Steven Aibor Dkhar
Journal:  J Pharmacol Pharmacother       Date:  2013-01
  9 in total

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