| Literature DB >> 22398575 |
Suado M Abdillahi1, Selma Balvanović, Maria Baumgarten, Matthias Mörgelin.
Abstract
Collagen type VI is a subepithelial extracellular matrix component in airways and an adhesive substrate for oral pathogens [Bober et al.: J Innate Immun 2010;2:160-166]. Here, we report that collagen VI displays a dose-dependent antimicrobial activity against group A, C, and G streptococci by membrane disruption in physiological conditions. The data disclose previously unrecognized aspects of the extracellular matrix in innate host defense.Mesh:
Substances:
Year: 2012 PMID: 22398575 PMCID: PMC6741453 DOI: 10.1159/000335239
Source DB: PubMed Journal: J Innate Immun ISSN: 1662-811X Impact factor: 7.349