| Literature DB >> 22398014 |
Pichika Chantrathammachart1, Rafal Pawlinski.
Abstract
Sickle cell anemia is an inherited hematologic disorder associated with hemolytic and vaso-occlusive complications. An activation of coagulation is also a prominent feature of sickle cell anemia. Growing evidence indicates that coagulation may contribute to the inflammation and vascular injury in sickle cell anemia. This review focuses on tissue factor expression and its contribution to the activation of coagulation, thrombosis and vascular inflammation in sickle cell anemia.Entities:
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Year: 2012 PMID: 22398014 PMCID: PMC3335974 DOI: 10.1016/j.thromres.2012.02.038
Source DB: PubMed Journal: Thromb Res ISSN: 0049-3848 Impact factor: 3.944