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Literature DB >> 22396878

From bench to bedside: unique challenges of treating epilepsy in the aging brain.

Lee A Shapiro¹.

Abstract

Entities: Disease

Year: 2011 PMID： 22396878 PMCID： PMC3295069

Source DB: PubMed Journal: Aging Dis ISSN： 2152-5250 Impact factor: 6.745

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21 in total

1. Axon sprouting in a model of temporal lobe epilepsy creates a predominantly excitatory feedback circuit.

Authors: Paul S Buckmaster; Guo Feng Zhang; Ruth Yamawaki
Journal: J Neurosci Date: 2002-08-01 Impact factor: 6.167

2. Aging-induced Seizure-related Changes to the Hippocampal Mossy Fiber Pathway in Forebrain Specific BDNF Overexpressing Mice.

Authors: Kate L Weidner; Jeffrey H Goodman; Kathryn K Chadman; Daniel P McCloskey
Journal: Aging Dis Date: 2011-08-30 Impact factor: 6.745

3. Seizure-induced Increased Neurogenesis Occurs in the Dentate Gyrus of Aged Sprague-Dawley Rats.

Authors: Lee A Shapiro; Lulu Wang; Pooja Upadhyaya; Charles E Ribak
Journal: Aging Dis Date: 2011-08-30 Impact factor: 6.745

4. Pathophysiological considerations of seizures, epilepsy, and status epilepticus in the elderly.

Authors: Rebecca M Verellen; Jose E Cavazos
Journal: Aging Dis Date: 2011-08-30 Impact factor: 6.745

5. Electrical and Pharmacological Stimuli Reveal a Greater Susceptibility for CA3 Network Excitability in Hippocampal Slices from Aged vs. Adult Fischer 344 Rats.

Authors: Daniel J Kanak; Ryan T Jones; Ashish Tokhi; Amy L Willingham; Hitten P Zaveri; Gregory M Rose; Peter R Patrylo
Journal: Aging Dis Date: 2011-08-30 Impact factor: 6.745

6. Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes.

Authors: Ashok K Shetty; Bharathi Hattiangady; Geetha A Shetty
Journal: Glia Date: 2005-08-15 Impact factor: 7.452

From bench to bedside: unique challenges of treating epilepsy in the aging brain.

1. Axon sprouting in a model of temporal lobe epilepsy creates a predominantly excitatory feedback circuit.

2. Aging-induced Seizure-related Changes to the Hippocampal Mossy Fiber Pathway in Forebrain Specific BDNF Overexpressing Mice.

3. Seizure-induced Increased Neurogenesis Occurs in the Dentate Gyrus of Aged Sprague-Dawley Rats.

4. Pathophysiological considerations of seizures, epilepsy, and status epilepticus in the elderly.

5. Electrical and Pharmacological Stimuli Reveal a Greater Susceptibility for CA3 Network Excitability in Hippocampal Slices from Aged vs. Adult Fischer 344 Rats.

6. Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes.

7. Effects of age on kindling and kindled seizure-induced increase of benzodiazepine receptor binding.

Review 8. Descriptive epidemiology of epilepsy: contributions of population-based studies from Rochester, Minnesota.

Review 9. Current treatment strategies in selected situations in epilepsy.

10. Status epilepticus in children, adults, and the elderly.

Review 1. Animal Models of Epilepsy: A Phenotype-oriented Review.