Literature DB >> 22396450

Minireview: animal models and mechanisms of ovarian cancer development.

Lisa K Mullany1, JoAnne S Richards.   

Abstract

Ovarian cancer in women is a complex and deadly disease, where the molecular events that initiate and control tumor formation remain poorly defined. Therefore, mouse models provide one approach for determining the mechanisms by which specific oncogenic factors cause ovarian surface epithelial cell and granulosa cell transformation. This minireview summarizes the phenotypes of current mouse models that have been generated and some of the underlying mechanisms they have provided.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22396450      PMCID： PMC3320247          DOI： 10.1210/en.2011-2121

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


  62 in total

Review 1.  Ovarian surface epithelium: biology, endocrinology, and pathology.

Authors:  N Auersperg; A S Wong; K C Choi; S K Kang; P C Leung
Journal:  Endocr Rev       Date:  2001-04       Impact factor: 19.871

2.  Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer.

Authors:  Daniela M Dinulescu; Tan A Ince; Bradley J Quade; Sarah A Shafer; Denise Crowley; Tyler Jacks
Journal:  Nat Med       Date:  2004-12-26       Impact factor: 53.440

Review 3.  Bone morphogenetic protein signaling transcription factor (SMAD) function in granulosa cells.

Authors:  Stephanie A Pangas
Journal:  Mol Cell Endocrinol       Date:  2011-07-07       Impact factor: 4.102

4.  Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy.

Authors:  Abhimanyu S Paraskar; Shivani Soni; Kenneth T Chin; Padmaparna Chaudhuri; Katherine W Muto; Julia Berkowitz; Michael W Handlogten; Nathan J Alves; Basar Bilgicer; Daniela M Dinulescu; Raghunath A Mashelkar; Shiladitya Sengupta
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-23       Impact factor: 11.205

5.  Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testis.

Authors:  Alexandre Boyer; Marilène Paquet; Marie-Noëlle Laguë; Louis Hermo; Derek Boerboom
Journal:  Carcinogenesis       Date:  2009-02-23       Impact factor: 4.944

6.  Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression.

Authors:  Marie-Noëlle Laguë; Marilène Paquet; Heng-Yu Fan; M Johanna Kaartinen; Simon Chu; Soazik P Jamin; Richard R Behringer; Peter J Fuller; Andrew Mitchell; Monique Doré; Louis M Huneault; Joanne S Richards; Derek Boerboom
Journal:  Carcinogenesis       Date:  2008-08-06       Impact factor: 4.944

7.  Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing.

Authors:  Kwok-Kin Wong; Richard S Maser; Robert M Bachoo; Jayant Menon; Daniel R Carrasco; Yansong Gu; Frederick W Alt; Ronald A DePinho
Journal:  Nature       Date:  2003-01-22       Impact factor: 49.962

8.  Targeted disruption of Pten in ovarian granulosa cells enhances ovulation and extends the life span of luteal cells.

Authors:  Heng-Yu Fan; Zhilin Liu; Nicola Cahill; JoAnne S Richards
Journal:  Mol Endocrinol       Date:  2008-07-07

9.  Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

Authors:  Rong Wu; Neali Hendrix-Lucas; Rork Kuick; Yali Zhai; Donald R Schwartz; Aytekin Akyol; Samir Hanash; David E Misek; Hidetaka Katabuchi; Bart O Williams; Eric R Fearon; Kathleen R Cho
Journal:  Cancer Cell       Date:  2007-04       Impact factor: 31.743

10.  Uncoupling cancer mutations reveals critical timing of p53 loss in sarcomagenesis.

Authors:  Nathan P Young; Denise Crowley; Tyler Jacks
Journal:  Cancer Res       Date:  2011-04-21       Impact factor: 12.701
View more
  28 in total

1.  Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer.

Authors:  Wei-Wei Pan; Jian-Jie Zhou; Chao Yu; Ying Xu; Lian-Jun Guo; Hai-Yi Zhang; Dawang Zhou; Fang-Zhou Song; Heng-Yu Fan
Journal:  J Biol Chem       Date:  2013-08-30       Impact factor: 5.157

2.  Follicle Depletion Provides a Permissive Environment for Ovarian Carcinogenesis.

Authors:  Ying Wang; Kathy Qi Cai; Elizabeth R Smith; Toni M Yeasky; Robert Moore; Parvin Ganjei-Azar; Andres J Klein-Szanto; Andrew K Godwin; Thomas C Hamilton; Xiang-Xi Xu
Journal:  Mol Cell Biol       Date:  2016-08-26       Impact factor: 4.272

3.  FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development.

Authors:  Zhilin Liu; Yi A Ren; Stephanie A Pangas; Jaye Adams; Wei Zhou; Diego H Castrillon; Dagmar Wilhelm; JoAnne S Richards
Journal:  Mol Endocrinol       Date:  2015-06-10

4.  Migration dynamics of ovarian epithelial cells on micro-fabricated image-based models of normal and malignant stroma.

Authors:  Samuel Alkmin; Rebecca Brodziski; Haleigh Simon; Daniel Hinton; Randall H Goldsmith; Manish Patankar; Paul J Campagnola
Journal:  Acta Biomater       Date:  2019-09-27       Impact factor: 8.947

5.  PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation.

Authors:  Angela Russo; Austin A Czarnecki; Matthew Dean; Dimple A Modi; Daniel D Lantvit; Laura Hardy; Seth Baligod; David A Davis; Jian-Jun Wei; Joanna E Burdette
Journal:  Oncogene       Date:  2018-01-25       Impact factor: 9.867

6.  Charged-Iron-Particles Found in Galactic Cosmic Rays are Potent Inducers of Epithelial Ovarian Tumors.

Authors:  Birendra Mishra; Gregory W Lawson; Ryan Ripperdan; Laura Ortiz; Ulrike Luderer
Journal:  Radiat Res       Date:  2018-05-21       Impact factor: 2.841

7.  Mitochondrial division inhibitor 1 (mdivi-1) enhances death receptor-mediated apoptosis in human ovarian cancer cells.

Authors:  Jingnan Wang; Karyn Hansen; Robert Edwards; Bennett Van Houten; Wei Qian
Journal:  Biochem Biophys Res Commun       Date:  2014-11-13       Impact factor: 3.575

Review 8.  Minireview: human ovarian cancer: biology, current management, and paths to personalizing therapy.

Authors:  Ignacio Romero; Robert C Bast
Journal:  Endocrinology       Date:  2012-03-13       Impact factor: 4.736

9.  In Utero Exposure to Benzo[a]pyrene Induces Ovarian Mutations at Doses That Deplete Ovarian Follicles in Mice.

Authors:  Ulrike Luderer; Matthew J Meier; Gregory W Lawson; Marc A Beal; Carole L Yauk; Francesco Marchetti
Journal:  Environ Mol Mutagen       Date:  2018-12-21       Impact factor: 3.216

10.  Polarity switching mass spectrometry imaging of healthy and cancerous hen ovarian tissue sections by infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI).

Authors:  Milad Nazari; David C Muddiman
Journal:  Analyst       Date:  2016-01-21       Impact factor: 4.616
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.