AIMS: To evaluate the utility of the International Prostate Symptom Score (IPSS) and the LUTS Tool when assessing lower urinary tract symptoms (LUTS). Secondary objectives were to examine associations of LUTS and treatment seeking. METHODS: Analyses were performed using EpiLUTS data, a population-based, cross-sectional, Internet survey of men and women (aged ≥40) in Sweden, UK, and US with a sample of 30,000 participants. Participants completed the IPSS and the LUTS Tool. Prevalence rates of symptoms captured by the LUTS Tool were compared using IPSS summary scores: 0, 1-7, 8-19, and ≥20. LUTS Tool subscale scores were calculated. Pearson correlations between the LUTS Tool symptoms and subscales and IPSS symptoms were performed. Logistic regressions evaluated the associations of IPSS scores and LUTS Tool subscales with treatment seeking for LUTS. RESULTS: The IPSS did not assess some symptoms (i.e., incontinence) for which there was a high prevalence among participants. Correlations between the 7 symptoms assessed by the IPSS and LUTS Tool were moderate to high ranging between 0.37 (nocturia women) and 0.77 (weak stream men), indicating concordance. While the LUTS Tool subscales and the total IPSS score were all significantly associated with treatment seeking, the LUTS Tool OAB subscale in men and Voiding subscale in women most strongly predicted treatment seeking. CONCLUSION: LUTS that are excluded from the IPSS, most notably incontinence, were prevalent even among mildly symptomatic participants. Since storage symptoms appear to drive treatment seeking, identifying, and treating these symptoms is essential when caring for patients with LUTS.
AIMS: To evaluate the utility of the International Prostate Symptom Score (IPSS) and the LUTS Tool when assessing lower urinary tract symptoms (LUTS). Secondary objectives were to examine associations of LUTS and treatment seeking. METHODS: Analyses were performed using EpiLUTS data, a population-based, cross-sectional, Internet survey of men and women (aged ≥40) in Sweden, UK, and US with a sample of 30,000 participants. Participants completed the IPSS and the LUTS Tool. Prevalence rates of symptoms captured by the LUTS Tool were compared using IPSS summary scores: 0, 1-7, 8-19, and ≥20. LUTS Tool subscale scores were calculated. Pearson correlations between the LUTS Tool symptoms and subscales and IPSS symptoms were performed. Logistic regressions evaluated the associations of IPSS scores and LUTS Tool subscales with treatment seeking for LUTS. RESULTS: The IPSS did not assess some symptoms (i.e., incontinence) for which there was a high prevalence among participants. Correlations between the 7 symptoms assessed by the IPSS and LUTS Tool were moderate to high ranging between 0.37 (nocturiawomen) and 0.77 (weak stream men), indicating concordance. While the LUTS Tool subscales and the total IPSS score were all significantly associated with treatment seeking, the LUTS Tool OAB subscale in men and Voiding subscale in women most strongly predicted treatment seeking. CONCLUSION: LUTS that are excluded from the IPSS, most notably incontinence, were prevalent even among mildly symptomatic participants. Since storage symptoms appear to drive treatment seeking, identifying, and treating these symptoms is essential when caring for patients with LUTS.
Authors: Cindy L Amundsen; Margaret E Helmuth; Abigail R Smith; John O L DeLancey; Catherine S Bradley; Kathryn E Flynn; Kimberly S Kenton; H Henry Lai; David Cella; James W Griffith; Victor P Andreev; J Eric Jelovsek; Alice B Liu; Ziya Kirkali; Claire C Yang Journal: Neurourol Urodyn Date: 2019-11-25 Impact factor: 2.696
Authors: H Henry Lai; Margaret E Helmuth; Abigail R Smith; Jonathan B Wiseman; Brenda W Gillespie; Ziya Kirkali Journal: Urology Date: 2018-10-28 Impact factor: 2.649
Authors: Nazema Y Siddiqui; Jonathan B Wiseman; David Cella; Catherine S Bradley; H Henry Lai; Margaret E Helmuth; Abigail R Smith; James W Griffith; Cindy L Amundsen; Kimberly S Kenton; J Quentin Clemens; Karl J Kreder; Robert M Merion; Ziya Kirkali; John W Kusek; Anne P Cameron Journal: J Urol Date: 2018-05-03 Impact factor: 7.450
Authors: James W Griffith; Emily E Messersmith; Brenda W Gillespie; Jonathan B Wiseman; Kathryn E Flynn; Ziya Kirkali; John W Kusek; Tamara Bavendam; David Cella; Karl J Kreder; Jasmine J Nero; Maria E Corona; Catherine S Bradley; Kimberly S Kenton; Brian T Helfand; Robert M Merion; Kevin P Weinfurt Journal: J Urol Date: 2017-07-20 Impact factor: 7.450
Authors: Gang Liu; Victor P Andreev; Margaret E Helmuth; Claire C Yang; H Henry Lai; Abigail R Smith; Jonathan B Wiseman; Robert M Merion; Bradley A Erickson; David Cella; James W Griffith; John L Gore; John O L DeLancey; Ziya Kirkali Journal: J Urol Date: 2019-05-23 Impact factor: 7.450
Authors: Brian T Helfand; Victor P Andreev; Nazema Y Siddiqui; Gang Liu; Bradley A Erickson; Margaret E Helmuth; Susan K Lutgendorf; H Henry Lai; Ziya Kirkali Journal: Urology Date: 2019-03-25 Impact factor: 2.649
Authors: Kevin P Weinfurt; James W Griffith; Kathryn E Flynn; David Cella; Tamara Bavendam; Jonathan B Wiseman; Victor P Andreev; H Henry Lai; Alice B Liu; Ziya Kirkali; Anne P Cameron; Catherine S Bradley Journal: J Urol Date: 2019-06 Impact factor: 7.450
Authors: Anne P Cameron; Christina Lewicky-Gaupp; Abigail R Smith; Brian T Helfand; John L Gore; J Quentin Clemens; Claire C Yang; Nazema Y Siddiqui; H Henry Lai; James W Griffith; Victor P Andreev; Gang Liu; Kevin Weinfurt; Cindy L Amundsen; Catherine S Bradley; John W Kusek; Ziya Kirkali Journal: J Urol Date: 2017-10-28 Impact factor: 7.450