| Literature DB >> 22394509 |
Johanna Fraune1, Sabine Schramm, Manfred Alsheimer, Ricardo Benavente.
Abstract
The synaptonemal complex (SC) is a proteinaceous structure of chromosome bivalents whose assembly is indispensable for the successful progression of the first meiotic division of sexually reproducing organisms. In this mini-review we will focus on recent progress dealing with the composition and assembly of the mammalian SC. These advances mainly resulted from the systematic use of knockout mice for all known mammalian SC proteins as well as from protein polymerization studies performed in heterologous systems.Entities:
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Year: 2012 PMID： 22394509 DOI： 10.1016/j.yexcr.2012.02.018
Source DB: PubMed Journal: Exp Cell Res ISSN： 0014-4827 Impact factor: 3.905