INTRODUCTION: The accuracy of prediction equations for estimating resting energy expenditure (REE) in morbidly obese patients is unclear. The aim of this study was to compare the REE measured using bedside indirect calorimetry with commonly used prediction equations. METHODS: A total of 31 morbidly obese patients were studied. Pre-operative REE was measured with indirect calorimetry and compared with estimated REE using the Harris-Benedict and Schofield equations. All patients subsequently underwent a Roux-en-Y gastric bypass and measurements were repeated at six weeks and three months following surgery. RESULTS: The mean age of the patients was 47 years. The mean pre-operative body mass index was 46 kg/m(2). The mean REE measured using indirect calorimetry was 1,980 kcal/day. The estimated REE using the Harris-Benedict and Schofield formulae was 2,195 and 2,129 kcal/day respectively. The equations overestimated REE by 10% and 7%. Body weight and body mass index reduced significantly following Roux-en-Y gastric bypass. There was no significant change in measured REE over the three-month period. After weight loss the difference between the estimated and measured REE reduced to 1-3%. CONCLUSIONS: Prediction equations overestimate REE in morbidly obese patients. Their accuracy improved after surgery induced weight loss, confirming their validity for the normal weight population. Indirect calorimetry should be used in morbid obesity.
INTRODUCTION: The accuracy of prediction equations for estimating resting energy expenditure (REE) in morbidly obesepatients is unclear. The aim of this study was to compare the REE measured using bedside indirect calorimetry with commonly used prediction equations. METHODS: A total of 31 morbidly obesepatients were studied. Pre-operative REE was measured with indirect calorimetry and compared with estimated REE using the Harris-Benedict and Schofield equations. All patients subsequently underwent a Roux-en-Y gastric bypass and measurements were repeated at six weeks and three months following surgery. RESULTS: The mean age of the patients was 47 years. The mean pre-operative body mass index was 46 kg/m(2). The mean REE measured using indirect calorimetry was 1,980 kcal/day. The estimated REE using the Harris-Benedict and Schofield formulae was 2,195 and 2,129 kcal/day respectively. The equations overestimated REE by 10% and 7%. Body weight and body mass index reduced significantly following Roux-en-Y gastric bypass. There was no significant change in measured REE over the three-month period. After weight loss the difference between the estimated and measured REE reduced to 1-3%. CONCLUSIONS: Prediction equations overestimate REE in morbidly obesepatients. Their accuracy improved after surgery induced weight loss, confirming their validity for the normal weight population. Indirect calorimetry should be used in morbid obesity.
Authors: Manfred J Müller; Anja Bosy-Westphal; Susanne Klaus; Georg Kreymann; Petra M Lührmann; Monika Neuhäuser-Berthold; Rudolf Noack; Karl M Pirke; Petra Platte; Oliver Selberg; Jochen Steiniger Journal: Am J Clin Nutr Date: 2004-11 Impact factor: 7.045
Authors: Torsten Olbers; Sofia Björkman; Ak Lindroos; Almantas Maleckas; Lars Lönn; Lars Sjöström; Hans Lönroth Journal: Ann Surg Date: 2006-11 Impact factor: 12.969
Authors: O E Owen; J L Holup; D A D'Alessio; E S Craig; M Polansky; K J Smalley; E C Kavle; M C Bushman; L R Owen; M A Mozzoli Journal: Am J Clin Nutr Date: 1987-12 Impact factor: 7.045
Authors: Nuria Martínez-Lozano; Gloria Maria Barraco; Rafael Rios; Maria José Ruiz; Asta Tvarijonaviciute; Paul Fardy; Juan Antonio Madrid; Marta Garaulet Journal: Sci Rep Date: 2020-10-07 Impact factor: 4.379