Literature DB >> 22391210

The cyclin K/Cdk12 complex: an emerging new player in the maintenance of genome stability.

Dalibor Blazek.   

Abstract

Entities:  

Year:  2012        PMID： 22391210      PMCID： PMC3335913          DOI： 10.4161/cc.11.6.19678

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  10 in total

1.  Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing.

Authors:  Zhi Jiang Zang; Choon Kiat Ong; Ioana Cutcutache; Willie Yu; Shen Li Zhang; Dachuan Huang; Lian Dee Ler; Karl Dykema; Anna Gan; Jiong Tao; Siyu Lim; Yujing Liu; P Andrew Futreal; Heike Grabsch; Kyle A Furge; Liang Kee Goh; Steve Rozen; Bin Tean Teh; Patrick Tan
Journal:  Cancer Res       Date:  2010-11-19       Impact factor: 12.701

2.  DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation.

Authors:  Manuel J Muñoz; M Soledad Pérez Santangelo; Maria P Paronetto; Manuel de la Mata; Federico Pelisch; Stéphanie Boireau; Kira Glover-Cutter; Claudia Ben-Dov; Matías Blaustein; Juan J Lozano; Gregory Bird; David Bentley; Edouard Bertrand; Alberto R Kornblihtt
Journal:  Cell       Date:  2009-05-15       Impact factor: 41.582

3.  Budding yeast CTDK-I is required for DNA damage-induced transcription.

Authors:  Denis Ostapenko; Mark J Solomon
Journal:  Eukaryot Cell       Date:  2003-04

4.  The SET2-RPB1 interaction domain of human RECQ5 is important for transcription-associated genome stability.

Authors:  Min Li; Xiaohua Xu; Yilun Liu
Journal:  Mol Cell Biol       Date:  2011-03-14       Impact factor: 4.272

5.  CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1.

Authors:  Bartlomiej Bartkowiak; Pengda Liu; Hemali P Phatnani; Nicholas J Fuda; Jeffrey J Cooper; David H Price; Karen Adelman; John T Lis; Arno L Greenleaf
Journal:  Genes Dev       Date:  2010-10-15       Impact factor: 11.361

6.  Identification and characterization of the CDK12/cyclin L1 complex involved in alternative splicing regulation.

Authors:  Hung-Hsi Chen; Yu-Chiuan Wang; Ming-Ji Fann
Journal:  Mol Cell Biol       Date:  2006-04       Impact factor: 4.272

7.  A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability.

Authors:  Renee D Paulsen; Deena V Soni; Roy Wollman; Angela T Hahn; Muh-Ching Yee; Anna Guan; Jayne A Hesley; Steven C Miller; Evan F Cromwell; David E Solow-Cordero; Tobias Meyer; Karlene A Cimprich
Journal:  Mol Cell       Date:  2009-07-31       Impact factor: 17.970

8.  The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes.

Authors:  Dalibor Blazek; Jiri Kohoutek; Koen Bartholomeeusen; Eric Johansen; Petra Hulinkova; Zeping Luo; Peter Cimermancic; Jernej Ule; B Matija Peterlin
Journal:  Genes Dev       Date:  2011-10-15       Impact factor: 11.361

9.  Integrated genomic analyses of ovarian carcinoma.

Authors: 
Journal:  Nature       Date:  2011-06-29       Impact factor: 49.962

10.  HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.

Authors:  P R Benusiglio; P D Pharoah; P L Smith; F Lesueur; D Conroy; R N Luben; G Dew; C Jordan; A Dunning; D F Easton; B A J Ponder
Journal:  Br J Cancer       Date:  2006-11-21       Impact factor: 7.640
  10 in total
  13 in total

1.  Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas.

Authors:  Bartlomiej Bartkowiak; Christopher Yan; Arno L Greenleaf
Journal:  Biochim Biophys Acta       Date:  2015-07-17

2.  CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells.

Authors:  C Delehouzé; K Godl; N Loaëc; C Bruyère; N Desban; N Oumata; H Galons; T I Roumeliotis; E G Giannopoulou; J Grenet; D Twitchell; J Lahti; N Mouchet; M-D Galibert; S D Garbis; L Meijer
Journal:  Oncogene       Date:  2013-12-09       Impact factor: 9.867

3.  Quantitative Mass Spectrometry to Interrogate Proteomic Heterogeneity in Metastatic Lung Adenocarcinoma and Validate a Novel Somatic Mutation CDK12-G879V.

Authors:  Xu Zhang; Khoa Dang Nguyen; Paul A Rudnick; Nitin Roper; Emily Kawaler; Tapan K Maity; Shivangi Awasthi; Shaojian Gao; Romi Biswas; Abhilash Venugopalan; Constance M Cultraro; David Fenyö; Udayan Guha
Journal:  Mol Cell Proteomics       Date:  2019-01-07       Impact factor: 5.911

4.  Ovarian cancer-associated mutations disable catalytic activity of CDK12, a kinase that promotes homologous recombination repair and resistance to cisplatin and poly(ADP-ribose) polymerase inhibitors.

Authors:  Poorval M Joshi; Shari L Sutor; Catherine J Huntoon; Larry M Karnitz
Journal:  J Biol Chem       Date:  2014-02-19       Impact factor: 5.157

5.  Cyclin K goes with Cdk12 and Cdk13.

Authors:  Jiri Kohoutek; Dalibor Blazek
Journal:  Cell Div       Date:  2012-04-18       Impact factor: 5.130

6.  Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex.

Authors:  Kingsley M Ekumi; Hana Paculova; Tina Lenasi; Vendula Pospichalova; Christian A Bösken; Jana Rybarikova; Vitezslav Bryja; Matthias Geyer; Dalibor Blazek; Matjaz Barboric
Journal:  Nucleic Acids Res       Date:  2015-02-20       Impact factor: 16.971

Review 7.  Targeting CDK9 for Anti-Cancer Therapeutics.

Authors:  Ranadip Mandal; Sven Becker; Klaus Strebhardt
Journal:  Cancers (Basel)       Date:  2021-05-01       Impact factor: 6.639

8.  Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage.

Authors:  Dechen Fu; Fred Duafalia Dudimah; Jun Zhang; Anna Pickering; Jayabal Paneerselvam; Manikandan Palrasu; Hong Wang; Peiwen Fei
Journal:  Cell Cycle       Date:  2013-02-06       Impact factor: 4.534

Review 9.  Lost in transcription: molecular mechanisms that control HIV latency.

Authors:  Ran Taube; Matija Peterlin
Journal:  Viruses       Date:  2013-03-21       Impact factor: 5.048

Review 10.  Regulation of CDK9 activity by phosphorylation and dephosphorylation.

Authors:  Sergei Nekhai; Michael Petukhov; Denitra Breuer
Journal:  Biomed Res Int       Date:  2014-01-12       Impact factor: 3.411
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