BACKGROUND: Although the prevalence of aspirin-exacerbated respiratory disease (AERD) in western populations is high, AERD is rather rare in China, and few related studies have been published to date. METHODS: We performed a prospective cohort investigation on the incidence of AERD in patients with chronic rhinosinusitis (CRS) in southern China. A literature search of the China Academic Journal Network Publishing Database was conducted to obtain an overview of the incidence of AERD in the Chinese population, and previous studies on the incidence of AERD were reviewed. RESULTS: We found 2 patients with aspirin hypersensitivity among 351 consecutive CRS (309 with nasal polyps [NPs]) patients, suggesting a rate of 0.57% in the CRS population. Forty-five articles about AERD were obtained by Chinese-language literature searches. In total, 346 cases of AERD were reported during the past 30 years. CONCLUSION: Given the large population of NPs in China, the prevalence of AERD is very low, and this may be related to the reduced levels of nasal tissue eosinophilia and subsequent low asthma comorbidity.
BACKGROUND: Although the prevalence of aspirin-exacerbated respiratory disease (AERD) in western populations is high, AERD is rather rare in China, and few related studies have been published to date. METHODS: We performed a prospective cohort investigation on the incidence of AERD in patients with chronic rhinosinusitis (CRS) in southern China. A literature search of the China Academic Journal Network Publishing Database was conducted to obtain an overview of the incidence of AERD in the Chinese population, and previous studies on the incidence of AERD were reviewed. RESULTS: We found 2 patients with aspirinhypersensitivity among 351 consecutive CRS (309 with nasal polyps [NPs]) patients, suggesting a rate of 0.57% in the CRS population. Forty-five articles about AERD were obtained by Chinese-language literature searches. In total, 346 cases of AERD were reported during the past 30 years. CONCLUSION: Given the large population of NPs in China, the prevalence of AERD is very low, and this may be related to the reduced levels of nasal tissue eosinophilia and subsequent low asthma comorbidity.
Authors: Eric Macy; Jonathan A Bernstein; Mariana C Castells; Sandra M Gawchik; Tak H Lee; Russell A Settipane; Ronald A Simon; Jeffrey Wald; Katharine M Woessner Journal: Ann Allergy Asthma Immunol Date: 2007-02 Impact factor: 6.347
Authors: Kelly A Zander; Milene T Saavedra; James West; Victor Scapa; Linda Sanders; Todd T Kingdom Journal: Am J Rhinol Allergy Date: 2009 May-Jun Impact factor: 2.467
Authors: A Fuentes-Beltrán; R Montes-Vizuet; E Valencia-Maqueda; M C Negrete-García; M de L García-Cruz; L M Teran Journal: Clin Exp Allergy Date: 2009-02-10 Impact factor: 5.018