| Literature DB >> 223871 |
M H Lin, D R Romsos, T Akera, G A Leveille.
Abstract
(3H)-Ouabain binding to liver and kidney preparations was utilized to estimate the number of Na+, K+-ATPase enzyme units in livers and kidneys from rats fed 2% corn oil supplemented or fat-free diets. The specific (3H)-ouabain binding in liver and kidney preparations from fatty acid deficient rats was increased approximately 40%, but the affinity of the binding sites for ouabain (Kd-value) remained unchanged. The increased concentration of Na+, K+-ATPase enzyme units observed in the essential fatty acid deficient rats may contribute to the reduced body fat accumulation and elevated heat production observed in these animals.Entities:
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Year: 1979 PMID： 223871 DOI： 10.1007/bf01968211
Source DB: PubMed Journal: Experientia ISSN： 0014-4754