Literature DB >> 22387032

The natural history of halo nevi: a retrospective case series.

Mouhammad Aouthmany1, Mara Weinstein, Matthew J Zirwas, Robert T Brodell.   

Abstract

BACKGROUND: The time period between onset of depigmentation around the halo nevus (HN) to complete resolution of the nevus and halo has not been well studied.
OBJECTIVE: We sought to better understand the natural history of the HN.
METHODS: A retrospective chart review of patients with a clinical diagnosis of HN selected from a private practice database (1994-2010) was performed. In all, 52 patients with 80 HN were identified. The current stage of the HN was determined by a follow-up questionnaire and physical examination of 36 patients with 56 HN.
RESULTS: Seven HN were excised. Of the remaining 49 HN, 51% (25) demonstrated no change in the halo or nevus after an average of 4.2 years; 14.3% (7) demonstrated partial nevus regression with persistence of the halo after an average of 6.7 years; 4.1% (2) demonstrated complete involution of the nevus with persistent halo depigmentation after an average of 7.7 years; 8.2% (4) demonstrated complete nevus involution with some repigmentation of the halo after an average of 11.8 years; 22.4% (11) demonstrated complete resolution of the nevus with complete repigmentation of the halo after an average of 7.8 years. LIMITATION: Some subjects were lost to follow-up. The time of initial HN onset was dependent on patient recall.
CONCLUSION: These results demonstrate that HN typically persist for a decade or longer. A subgroup may progress through stages of involution with a return to normal-appearing skin, but even these lesions persisted for an average of 7.8 years. Education about the prolonged natural history of HN may reassure patients and avoid unnecessary excision.
Copyright © 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

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Year:  2012        PMID: 22387032     DOI: 10.1016/j.jaad.2011.11.937

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  7 in total

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4.  Factors Associated with Development of Vitiligo in Patients with Halo Nevus.

Authors:  Hui Zhou; Liang-Cai Wu; Mu-Kai Chen; Qi-Man Liao; Ren-Xiang Mao; Jian-De Han
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5.  Recurrent halo nevus: Dermoscopy and confocal microscopy features.

Authors:  Ana Carolina Porto; Tatiana Pinto Blumetti; Raquel de Paula Ramos Castro; Clovis Antônio Lopes Pinto; Adriana Silveira Pessoa Mendes; João Pedreira Duprat Neto; Gisele Gargantini Rezze; Juliana Casagrande Tavoloni Braga
Journal:  JAAD Case Rep       Date:  2017-05-24

6.  Halo Nevi Are Not Trivial: About 2 Young Patients of Regressed Primary Melanoma That Simulates Halo Nevi.

Authors:  S De Schrijver; I Theate; O Vanhooteghem
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7.  Efficacy of 308-nm Monochromatic Excimer Light in the Management of Halo Nevi: An Open-Label, Pilot Study.

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  7 in total

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