Literature DB >> 22385442

Xenograft scaffold full-wrap reinforcement of Krackow achilles tendon repair.

Jacob M Wisbeck1, Brent G Parks, Lew C Schon.   

Abstract

Standard 4-strand repair of Achilles tendon tears is effective, but additional strength may be desirable in patients who are compromised or those with reruptures. Use of a xenograft scaffold has not been investigated biomechanically in Achilles tendon repair. This study compared stiffness, gap formation, and ultimate load to failure with Krackow repair vs Krackow repair augmented with xenograft scaffold in 6 matched pairs of fresh-frozen human lower extremities. The Achilles tendon was transected 4 cm above the calcaneal insertion. Specimens were randomized to receive standard Krackow repair or Krackow repair augmented with a porcine xenograft scaffold. The graft was wrapped around the repaired tendon, sutured to itself with 2-0 FiberWire (Arthrex, Naples, Florida), and attached to the tendon distally and proximally and then medially and laterally. Specimens were loaded for 200 cycles between 5 and 30 N. Load to 5-mm gapping and load to ultimate failure were measured. Xenograft scaffold augmentation of standard Krakow Achilles tendon repair was significantly stronger and stiffer than standard Krackow repair in a biomechanical model immediately after repair (39.0±8.8 vs 24.4±4.6 N/mm; P=.01). The augmented repair group had significantly higher load to ultimate failure than did the Krackow group (862.7±174.0 vs 479.5±65.5 N; P<.01). Biological factors remain to be investigated, but this augmentation method could provide additional strength in patients who are compromised or those with reruptures. Copyright 2012, SLACK Incorporated.

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Year:  2012        PMID: 22385442     DOI: 10.3928/01477447-20120222-41

Source DB:  PubMed          Journal:  Orthopedics        ISSN: 0147-7447            Impact factor:   1.390


  6 in total

Review 1.  Modified triple Kessler with least risk of elongation among Achilles tendon repair techniques: a systematic review and network meta-analysis of human cadaveric studies.

Authors:  Pedro Diniz; Jácome Pacheco; Ricardo M Fernandes; Hélder Pereira; Frederico Castelo Ferreira; Gino M M J Kerkhoffs
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2021-06-05       Impact factor: 4.342

2.  Transplantation of fetal instead of adult fibroblasts reduces the probability of ectopic ossification during tendon repair.

Authors:  Zhi Fang; Ting Zhu; Wei Liang Shen; Qiao Mei Tang; Jia Lin Chen; Zi Yin; Jun Feng Ji; Boon Chin Heng; Hong Wei Ouyang; Xiao Chen
Journal:  Tissue Eng Part A       Date:  2014-05-15       Impact factor: 3.845

3.  Biologics in Achilles tendon healing and repair: a review.

Authors:  Evan Shapiro; Daniel Grande; Mark Drakos
Journal:  Curr Rev Musculoskelet Med       Date:  2015-03

4.  Application of lariat lock catch knot suture in the achilles tendon rupture.

Authors:  Baocang Wang; Xiaona Feng; Ming Yan; Hui Wang; Yong Li
Journal:  Int J Clin Exp Med       Date:  2015-10-15

5.  Induced Remodeling of Porcine Tendons to Human Anterior Cruciate Ligaments by α-GAL Epitope Removal and Partial Cross-Linking.

Authors:  Kevin R Stone; Ann Walgenbach; Uri Galili
Journal:  Tissue Eng Part B Rev       Date:  2017-02-14       Impact factor: 6.389

6.  Development of a surgically optimized graft insertion suture technique to accommodate a tissue-engineered tendon in vivo.

Authors:  Prasad Sawadkar; Susan Alexander; Marten Tolk; Jason Wong; Duncan McGrouther; Laurent Bozec; Vivek Mudera
Journal:  Biores Open Access       Date:  2013-10
  6 in total

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