Literature DB >> 22382553

[Primary immune thrombocytopenia in adults: diagnostics and treatment consensus statement of the Austrian Society of Hematology and Oncology (ÖGHO)].

Ingrid Pabinger1, Günther Gastl, Michael Steurer, Siegfried Sormann, Michael Fillitz, Josef Friedl, Dietmar Geissler, Klaus Geissler, Richard Greil, Paul Knöbl, Sibylle Kozek-Langenecker, Peter Krippl, Paul Kyrle, Alois Lang, Werner Linkesch, Heinz Ludwig, Markus Müller, Simon Panzer, Elisabeth Pittermann, Josef Thaler, Ansgar Weltermann.   

Abstract

Immune Thrombocytopenia (ITP) is a rare and - in most patients - mild disease, but might be associated with severe or even life-threatening bleeding complications. The treatment of ITP has partly changed in recent years, due to new therapeutic options. International guidelines changed accordingly. This consensus statement by the Austrian Society of Hematology and Oncology (OEGHO) is not a new evaluation of the current evidence, but rather tries to discuss the available international guidelines and adapt them to the situation in Austria. The subject is primary ITP in adults only. Classification, epidemiology, clinical presentation and diagnostics of ITP, and especially the management of this disease, are discussed in detail. This includes current aspects of first, second, and third line therapies, splenectomy with its indications and contraindications, and the use of new therapeutic options like thrombopoetin receptor agonists (TRA).

Entities:  

Mesh:

Year:  2012        PMID: 22382553     DOI: 10.1007/s00508-012-0123-3

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN: 0043-5325            Impact factor:   1.704


  86 in total

1.  Suppression of in vitro megakaryocyte production by antiplatelet autoantibodies from adult patients with chronic ITP.

Authors:  Robert McMillan; Lei Wang; Aaron Tomer; Janet Nichol; Jeanne Pistillo
Journal:  Blood       Date:  2003-10-23       Impact factor: 22.113

2.  [Diagnosis and therapy of autoimmune thrombocytopenia. Recommendations of a joint Expert Group of DGHO, DGTI, DTH].

Authors:  Axel Matzdorff; Aristoteles Giagounidis; Andreas Greinacher; Erhard Hiller; Volker Kiefel; Hannes Müller-Beissenhirtz; Helmut Ostermann; Mathias Rummel; Ulrich J Sachs; Abdulgabar Salama
Journal:  Onkologie       Date:  2010-04-23

3.  The course of severe autoimmune thrombocytopenia in patients not undergoing splenectomy.

Authors:  Thomas Sailer; Klaus Lechner; Simon Panzer; Paul Alexander Kyrle; Ingrid Pabinger
Journal:  Haematologica       Date:  2006-08       Impact factor: 9.941

Review 4.  Autoimmune platelet destruction: idiopathic thrombocytopenic purpura.

Authors:  J G Kelton; S Gibbons
Journal:  Semin Thromb Hemost       Date:  1982-04       Impact factor: 4.180

5.  Therapeutic experience on 934 adults with idiopathic thrombocytopenic purpura: Multicentric Trial of the Cooperative Latin American group on Hemostasis and Thrombosis.

Authors:  J Pizzuto; R Ambriz
Journal:  Blood       Date:  1984-12       Impact factor: 22.113

6.  [Idiopathic thrombocytopenic purpura (Werlhof disease) and differential diagnosis from other thrombocytopenic hemorrhagic diatheses].

Authors:  Kim B Luley; Thomas Wagner
Journal:  Med Klin (Munich)       Date:  2009-05-15

7.  Massive platelet transfusion is a rapidly effective emergency treatment in patients with refractory autoimmune thrombocytopenia.

Authors:  Abdulgabar Salama; Holger Kiesewetter; Ulrich Kalus; Kamran Movassaghi; Oliver Meyer
Journal:  Thromb Haemost       Date:  2008-11       Impact factor: 5.249

8.  T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura.

Authors:  Bob Olsson; Per-Ola Andersson; Margareta Jernås; Stefan Jacobsson; Björn Carlsson; Lena M S Carlsson; Hans Wadenvik
Journal:  Nat Med       Date:  2003-08-24       Impact factor: 53.440

9.  Prospective screening of 205 patients with ITP, including diagnosis, serological markers, and the relationship between platelet counts, endogenous thrombopoietin, and circulating antithrombopoietin antibodies.

Authors:  Louis M Aledort; Catherine P M Hayward; Mon-Gy Chen; Janet L Nichol; James Bussel
Journal:  Am J Hematol       Date:  2004-07       Impact factor: 10.047

10.  Activity and safety profile of low-dose rituximab for the treatment of autoimmune cytopenias in adults.

Authors:  Drew Provan; Tom Butler; Maria Laura Evangelista; Sergio Amadori; Adrian C Newland; Roberto Stasi
Journal:  Haematologica       Date:  2007-12       Impact factor: 9.941

View more
  1 in total

1.  Management of Adult Patients with Primary Immune Thrombocytopenia (ITP) in Clinical Practice: A Consensus Approach of the Spanish ITP Expert Group.

Authors:  M Eva Mingot-Castellano; M Teresa Álvarez Román; Luis Fernando Fernández Fuertes; Tomás José González-López; José María Guinea de Castro; Isidro Jarque; M Fernanda López-Fernández; Maria Luisa Lozano; Blanca Sánchez González; David Valcárcel Ferreiras; José Ramón González Porras
Journal:  Adv Hematol       Date:  2019-08-22
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.