Literature DB >> 2238123

Evaluation of BCG at birth in the United Arab Emirates.

M R Sedaghatian1, I A Shana'a.   

Abstract

A total of 387 healthy full term infants who received BCG vaccination at birth were evaluated by the tuberculin PPD test at 6-8 weeks post vaccination. A total of 92% of these infants had visible BCG scars at that time. All infants were tested with PPD but only 264 returned for the test to be read. The tuberculin test was negative in 37 (14%) and of less than 5 mm induration in another 60 (23%) of the infants. The same pattern was observed in different nationalities. Of 11 infants with no BCG scar after vaccination, 3 had positive PPD reactions of more than 5 mm induration. There was a significant correlation between the size of the BCG scar and induration of tuberculin test P less than 0.001. The complications of the vaccination were minimal. We have observed 3 sterile abscesses at the site of BCG vaccination which resolved spontaneously. We think the available vaccine is safe and potent, and that the rate of BCG scar formation and of tuberculin conversion is higher than in most studies.

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Year:  1990        PMID: 2238123     DOI: 10.1016/0041-3879(90)90072-g

Source DB:  PubMed          Journal:  Tubercle        ISSN: 0041-3879


  7 in total

1.  Tuberculin response in preterm infants after BCG vaccination at birth.

Authors:  M R Sedaghatian; K Kardouni
Journal:  Arch Dis Child       Date:  1993-09       Impact factor: 3.791

2.  Clinical and immune impact of Mycobacterium bovis BCG vaccination scarring.

Authors:  Janine Jason; Lennox K Archibald; Okey C Nwanyanwu; Peter N Kazembe; Julie A Chatt; Elizabeth Norton; Hamish Dobbie; William R Jarvis
Journal:  Infect Immun       Date:  2002-11       Impact factor: 3.441

Review 3.  Safety and efficacy of neonatal vaccination.

Authors:  Alicia Demirjian; Ofer Levy
Journal:  Eur J Immunol       Date:  2009-01       Impact factor: 5.532

4.  Dual Bacillus Calmette-Guerin vaccination along the border communities of Angola and Namibia.

Authors:  Abubakar Sadiq Umar; Lusamba Kabamba
Journal:  J Family Med Prim Care       Date:  2016 Apr-Jun

5.  Determinants of Bacille Calmette-Guérin scarification in Danish children.

Authors:  Trine Mølbæk Jensen; Signe Kjeldgaard Jensen; Nina Marie Birk; Andreas Rieckmann; Thomas Hoffmann; Christine Stabell Benn; Dorthe Lisbeth Jeppesen; Ole Pryds; Thomas Nørrelykke Nissen
Journal:  Heliyon       Date:  2021-01-04

6.  Scar formation and tuberculin conversion following BCG vaccination in infants: A prospective cohort study.

Authors:  Sara S Dhanawade; Suhas G Kumbhar; Alka D Gore; Vijay N Patil
Journal:  J Family Med Prim Care       Date:  2015 Jul-Sep

7.  A systematic review of BCG vaccination policies among high-risk groups in low TB-burden countries: implications for vaccination strategy in Canadian indigenous communities.

Authors:  Lena Faust; Yoko Schreiber; Natalie Bocking
Journal:  BMC Public Health       Date:  2019-11-11       Impact factor: 3.295

  7 in total

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