Literature DB >> 22379315

Ophthalmic considerations in cleft lip and palate patients.

Sonal Anchlia, Krishna Shama Rao, Krishnamurthy Bonanthaya, B Anupama, I Vittal Nayak.   

Abstract

Cleft lip and palate (CL and P) represents the second most frequently occurring congenital deformity after clubfoot deformity. CL and P could be associated with many other structural abnormalities of the adjacent vital structures of the face. In this study, an attempt was made to identify the abnormalities of the ocular structures seen in patients with isolated CL and P as well as in those with syndromic CL and P. Of the 322 patients with cleft lip and palate screened, 27 (8.3%) had ocular abnormalities. Totally 47 ocular defects were identified in 27 patients. Abnormalities of the eyelid were the commonest accounting for 22% of the total defects (11/47), which includes symblepharon, ectropion, lid colobomas, euryblepharon and ptosis. Second commonest abnormality was squint 8/47 (17%) followed by orbital defects 8/47 (17%) (Telecanthus and Hypertelorism). Abnormalities of the nasolacrimal apparatus 3/47 (6%), refractive errors 7/47 (15%), dermoids 4/47 (6%), cataract 2/47 (4%) and retinal colobomas 2/47 (4%) constituted the rest. Thus, children with cleft lip and palate should be assessed as soon as possible after birth by a multidisciplinary team involving the Pediatrician, Ophthalmologist and specialists from Maxillofacial, ENT and Plastic surgery. The medical problems in this group of children are global and therefore, should not be looked at in isolation.

Entities:  

Keywords:  Cleft lip and palate; Congenital deformities; Ocular abnormalities

Year:  2011        PMID: 22379315      PMCID: PMC3177494          DOI: 10.1007/s12663-010-0058-z

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  5 in total

1.  The aetiology and surgery of cleft palate with micrognathia.

Authors:  D Poswillo
Journal:  Ann R Coll Surg Engl       Date:  1968-08       Impact factor: 1.891

2.  Abnormal phenylalanine loading tests in mothers of children with cleft defects.

Authors:  P M Tocci; B Beber
Journal:  Cleft Palate J       Date:  1970-04

3.  Malformations recorded on birth certificates following A2 influenza epidemics.

Authors:  I Leck; S Hay; J J Witte; J C Greene
Journal:  Public Health Rep       Date:  1969-11       Impact factor: 2.792

4.  Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene.

Authors:  M Tassabehji; A P Read; V E Newton; R Harris; R Balling; P Gruss; T Strachan
Journal:  Nature       Date:  1992-02-13       Impact factor: 49.962

Review 5.  Teratogens and craniofacial malformations: relationships to cell death.

Authors:  K K Sulik; C S Cook; W S Webster
Journal:  Development       Date:  1988       Impact factor: 6.868

  5 in total
  4 in total

1.  Birth Defect Co-Occurrence Patterns Among Infants With Cleft Lip and/or Palate.

Authors:  Maria Luisa Navarro Sanchez; Renata H Benjamin; Laura E Mitchell; Peter H Langlois; Mark A Canfield; Michael D Swartz; Angela E Scheuerle; Daryl A Scott; Hope Northrup; Christian P Schaaf; Joseph W Ray; Scott D McLean; Han Chen; Philip J Lupo; A J Agopian
Journal:  Cleft Palate Craniofac J       Date:  2021-04-28

2.  Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.

Authors:  Robert J Lipinski; Hunter T Holloway; Shonagh K O'Leary-Moore; Jacob J Ament; Stephen J Pecevich; Gary P Cofer; Francois Budin; Joshua L Everson; G Allan Johnson; Kathleen K Sulik
Journal:  PLoS One       Date:  2014-07-21       Impact factor: 3.240

3.  Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate.

Authors:  Ivana Bukova; Katarzyna Izabela Szczerkowska; Michaela Prochazkova; Inken M Beck; Jan Prochazka; Radislav Sedlacek
Journal:  Front Cell Dev Biol       Date:  2021-06-02

4.  Awareness of feeding, growth and development among mothers of infants with cleft lip and/or palate.

Authors:  Parakrama Wijekoon; Thanuja Herath; Rahini Mahendran
Journal:  Heliyon       Date:  2019-12-09
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.