Literature DB >> 22375845

Pyrrolidinyl peptide nucleic acid homologues: effect of ring size on hybridization properties.

Woraluk Mansawat1, Chotima Vilaivan, Árpád Balázs, David J Aitken, Tirayut Vilaivan.   

Abstract

The effect of ring size of four- to six-membered cyclic β-amino acid on the hybridization properties of pyrrolidinyl peptide nucleic acid with an alternating α/β peptide backbone is reported. The cyclobutane derivatives (acbcPNA) show the highest T(m) and excellent specificity with cDNA and RNA.

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Year:  2012        PMID： 22375845     DOI： 10.1021/ol300190u

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

Review 1.  Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications.

Authors:  Chaturong Suparpprom; Tirayut Vilaivan
Journal:  RSC Chem Biol       Date:  2022-03-18

2.  Efficient regio- and stereoselective access to novel fluorinated β-aminocyclohexanecarboxylates.

Authors:  Loránd Kiss; Melinda Nonn; Reijo Sillanpää; Santos Fustero; Ferenc Fülöp
Journal:  Beilstein J Org Chem       Date:  2013-06-17       Impact factor: 2.883

3.  Conformational Control of Dual Emission by Pyrrolidinyl PNA-DNA Hybrids.

Authors:  Sabrina Sezi; Reji Varghese; Tirayut Vilaivan; Hans-Achim Wagenknecht
Journal:  ChemistryOpen       Date:  2012-07-11       Impact factor: 2.911

4.  Synthesis and optical properties of pyrrolidinyl peptide nucleic acid carrying a clicked Nile red label.

Authors:  Nattawut Yotapan; Chayan Charoenpakdee; Pawinee Wathanathavorn; Boonsong Ditmangklo; Hans-Achim Wagenknecht; Tirayut Vilaivan
Journal:  Beilstein J Org Chem       Date:  2014-09-11       Impact factor: 2.883
  4 in total

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