Literature DB >> 22374650

Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations.

Marco Tischler1, Daichi Nasu, Martin Empting, Stefan Schmelz, Dirk W Heinz, Philipp Rottmann, Harald Kolmar, Gerd Buntkowsky, Daniel Tietze, Olga Avrutina.   

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Year:  2012        PMID： 22374650     DOI： 10.1002/anie.201108983

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  12 in total

1.  Protein production in Yarrowia lipolytica via fusion to the secreted lipase Lip2p.

Authors:  Thomas Hofmeyer; Siyavuya Ishmael Bulani; Julius Grzeschik; Simon Krah; Bernhard Glotzbach; Christina Uth; Olga Avrutina; Michael Brecht; Hans Ulrich Göringer; Petrus van Zyl; Harald Kolmar
Journal:  Mol Biotechnol       Date:  2014-01       Impact factor: 2.695

2.  Ruthenium-catalyzed cycloadditions of 1-haloalkynes with nitrile oxides and organic azides: synthesis of 4-haloisoxazoles and 5-halotriazoles.

Authors:  James S Oakdale; Rakesh K Sit; Valery V Fokin
Journal:  Chemistry       Date:  2014-07-24       Impact factor: 5.236

3.  Constrained Cyclic Peptides as Immunomodulatory Inhibitors of the CD2:CD58 Protein-Protein Interaction.

Authors:  Rushikesh Sable; Thomas Durek; Veena Taneja; David J Craik; Sandeep Pallerla; Ted Gauthier; Seetharama Jois
Journal:  ACS Chem Biol       Date:  2016-07-01       Impact factor: 5.100

4.  Systematic replacement of amides by 1,4-disubstituted[1,2,3]triazoles in Leu-enkephalin and the impact on the delta opioid receptor activity.

Authors:  Arnaud Proteau-Gagné; Kristina Rochon; Mélissa Roy; Pierre-Julien Albert; Brigitte Guérin; Louis Gendron; Yves L Dory
Journal:  Bioorg Med Chem Lett       Date:  2013-08-12       Impact factor: 2.823

5.  1,5-Disubstituted 1,2,3-Triazoles as Amide Bond Isosteres Yield Novel Tumor-Targeting Minigastrin Analogs.

Authors:  Nathalie M Grob; Roger Schibli; Martin Béhé; Ibai E Valverde; Thomas L Mindt
Journal:  ACS Med Chem Lett       Date:  2021-03-16       Impact factor: 4.345

6.  A grafted peptidomimetic for EGFR heterodimerization inhibition: Implications in NSCLC models.

Authors:  Sitanshu S Singh; George Mattheolabakis; Xin Gu; Sita Withers; Achyut Dahal; Seetharama Jois
Journal:  Eur J Med Chem       Date:  2021-02-23       Impact factor: 6.514

7.  Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1.

Authors:  Bernhard Glotzbach; Michael Reinwarth; Niklas Weber; Sebastian Fabritz; Michael Tomaszowski; Heiko Fittler; Andreas Christmann; Olga Avrutina; Harald Kolmar
Journal:  PLoS One       Date:  2013-10-11       Impact factor: 3.240

8.  Synthesis of Symmetrical Tetrameric Conjugates of the Radiolanthanide Chelator DOTPI for Application in Endoradiotherapy by Means of Click Chemistry.

Authors:  Alexander Wurzer; Adrienn Vágner; Dávid Horváth; Flóra Fellegi; Hans-Jürgen Wester; Ferenc K Kálmán; Johannes Notni
Journal:  Front Chem       Date:  2018-04-10       Impact factor: 5.221

Review 9.  1,4-Disubstituted 1,2,3-Triazoles as Amide Bond Surrogates for the Stabilisation of Linear Peptides with Biological Activity.

Authors:  Lisa-Maria Rečnik; Wolfgang Kandioller; Thomas L Mindt
Journal:  Molecules       Date:  2020-08-06       Impact factor: 4.411

10.  A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.

Authors:  Christian Schütz; Duy-Khiet Ho; Mostafa Mohamed Hamed; Ahmed Saad Abdelsamie; Teresa Röhrig; Christian Herr; Andreas Martin Kany; Katharina Rox; Stefan Schmelz; Lorenz Siebenbürger; Marius Wirth; Carsten Börger; Samir Yahiaoui; Robert Bals; Andrea Scrima; Wulf Blankenfeldt; Justus Constantin Horstmann; Rebekka Christmann; Xabier Murgia; Marcus Koch; Aylin Berwanger; Brigitta Loretz; Anna Katharina Herta Hirsch; Rolf Wolfgang Hartmann; Claus-Michael Lehr; Martin Empting
Journal:  Adv Sci (Weinh)       Date:  2021-03-18       Impact factor: 16.806
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