Literature DB >> 22374105

The Study Centre of the German Surgical Society: current trials and results.

Phillip Knebel1, Shafreena Kühn, Alexis B Ulrich, Markus W Büchler, Markus K Diener.   

Abstract

PURPOSE: This article provides an overview of current and completed multicentre trials and systematic reviews performed by the Study Centre of the German Surgical Society (SDGC).
BACKGROUND: The SDGC aims to transfer the concept of evidence-based medicine to surgery by planning, conducting and analyzing large national and international randomized multicentre trials concerning surgical issues. Every German surgeon may ask the SDGC for support to realize his clinical trial ideas. Another important task of the SDGC is the acquisition of trial funding from government institutions or industrial partners. DISCUSSION: Five multicentre randomized controlled trials (RCT) and 11 systematic reviews with meta-analyses have already been completed and published by the SDGC. Another seven RCTs are currently in the recruitment or follow up phase. A total of 2,500 patients in over 100 trial centres have participated so far.

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Year:  2012        PMID: 22374105     DOI: 10.1007/s00423-012-0922-z

Source DB:  PubMed          Journal:  Langenbecks Arch Surg        ISSN: 1435-2443            Impact factor:   3.445


  30 in total

Review 1.  Risk-benefit assessment of closed intra-abdominal drains after pancreatic surgery: a systematic review and meta-analysis assessing the current state of evidence.

Authors:  Markus K Diener; Keyvan Tadjalli-Mehr; Keyvan-Tadjalli Mehr; Moritz N Wente; Meinhard Kieser; Markus W Büchler; Christoph M Seiler
Journal:  Langenbecks Arch Surg       Date:  2010-10-21       Impact factor: 3.445

Review 2.  Systematic review and meta-analysis of the effect of portal triad clamping on outcome after hepatic resection.

Authors:  N N Rahbari; M N Wente; P Schemmer; M K Diener; K Hoffmann; E Motschall; J Schmidt; J Weitz; M W Büchler
Journal:  Br J Surg       Date:  2008-04       Impact factor: 6.939

3.  [Systematic reviews and meta-analyses in surgery].

Authors:  M K Diener; C M Seiler; G Antes
Journal:  Chirurg       Date:  2007-10       Impact factor: 0.955

Review 4.  Surgical evaluation and knowledge transfer--methods of clinical research in surgery.

Authors:  Markus K Diener; Thomas Simon; Markus W Büchler; Christoph M Seiler
Journal:  Langenbecks Arch Surg       Date:  2011-03-22       Impact factor: 3.445

5.  Surgical practice is evidence based.

Authors:  N Howes; L Chagla; M Thorpe; P McCulloch
Journal:  Br J Surg       Date:  1997-09       Impact factor: 6.939

6.  Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial.

Authors:  Markus K Diener; Christoph M Seiler; Inga Rossion; Jörg Kleeff; Matthias Glanemann; Giovanni Butturini; Ales Tomazic; Christiane J Bruns; Olivier R C Busch; Stefan Farkas; Orlin Belyaev; John P Neoptolemos; Christopher Halloran; Tobias Keck; Marco Niedergethmann; Klaus Gellert; Helmut Witzigmann; Otto Kollmar; Peter Langer; Ulrich Steger; Jens Neudecker; Frederik Berrevoet; Silke Ganzera; Markus M Heiss; Steffen P Luntz; Thomas Bruckner; Meinhard Kieser; Markus W Büchler
Journal:  Lancet       Date:  2011-04-30       Impact factor: 79.321

7.  Interrupted or continuous slowly absorbable sutures for closure of primary elective midline abdominal incisions: a multicenter randomized trial (INSECT: ISRCTN24023541).

Authors:  Christoph M Seiler; Thomas Bruckner; Markus K Diener; Armine Papyan; Henriette Golcher; Christoph Seidlmayer; Annette Franck; Meinhard Kieser; Markus W Büchler; Hanns-Peter Knaebel
Journal:  Ann Surg       Date:  2009-04       Impact factor: 12.969

8.  Hand-suture versus stapling for closure of loop ileostomy: HASTA-Trial: a study rationale and design for a randomized controlled trial.

Authors:  Thorsten Löffler; Christoph M Seiler; Inga Rossion; Thomas Kijak; Oliver Thomusch; Renè Hodina; Matthias Krüger; Thomas Simon; Thomas Bruckner; Meinhard Kieser; Markus W Büchler; Jürgen Weitz
Journal:  Trials       Date:  2011-02-08       Impact factor: 2.279

9.  Protocol design and current status of CLIVIT: a randomized controlled multicenter relevance trial comparing clips versus ligatures in thyroid surgery.

Authors:  C M Seiler; B E Fröhlich; J A Veit; E Gazyakan; M N Wente; C Wollermann; A Deckert; S Witte; N Victor; M W Buchler; H P Knaebel
Journal:  Trials       Date:  2006-09-01       Impact factor: 2.279

10.  Comparison of total parathyroidectomy without autotransplantation and without thymectomy versus total parathyroidectomy with autotransplantation and with thymectomy for secondary hyperparathyroidism: TOPAR PILOT-Trial.

Authors:  Katja Schlosser; Johannes A Veit; Stefan Witte; Emilio Domínguez Fernández; Norbert Victor; Hans-Peter Knaebel; Christoph M Seiler; Matthias Rothmund
Journal:  Trials       Date:  2007-09-18       Impact factor: 2.279

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  4 in total

1.  [Rotating physician in CHIR-Net. Evaluation of the curriculum].

Authors:  P Knöll; J Oppermann; J Vehreschild; F Beyer; T Kaulhausen; J Siewe; G Stein; C Otto; O Cornely; P Eysel; H Wyen; V Jakob; E Neugebauer; K Zarghooni
Journal:  Chirurg       Date:  2013-12       Impact factor: 0.955

2.  Future perspectives for surgical research in Germany.

Authors:  Markus K Diener; Michael D Menger; Joachim Jähne; Hans-Detlev Saeger; Ernst Klar
Journal:  Langenbecks Arch Surg       Date:  2014-03-11       Impact factor: 3.445

Review 3.  The future of trials in surgical oncology.

Authors:  Peter Naredi; Michael P La Quaglia
Journal:  Nat Rev Clin Oncol       Date:  2015-04-14       Impact factor: 66.675

4.  Number of published randomized controlled multi center trials testing pharmacological interventions or devices is increasing in both medical and surgical specialties.

Authors:  Anne Kjaergaard Danielsen; Cecilie Okholm; Hans-Christian Pommergaard; Jakob Burcharth; Jacob Rosenberg
Journal:  PLoS One       Date:  2014-07-14       Impact factor: 3.240

  4 in total

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