Literature DB >> 22370924

Subacute steroid-induced paraparesis: surgical treatment of a devastating "invisible" side effect.

M Javad Mirzayan1, M Javad Mirzayan1, Thomas Goessling, Tobias Huefner, Joachim K Krauss.   

Abstract

PURPOSE: To emphasize an underestimated side effect following long-term use of steroids.
METHODS: We report on surgical treatment of two patients with serious neurologic deficits caused by epidural spinal lipoma following long-term intake of cortisone.
RESULTS: Early decompression of the spinal cord by removal of epidural lipoma was the most effective treatment in these patients with progressive symptoms.
CONCLUSION: Diagnostic work-up of such patients should include early spinal MRI resulting in surgical intervention, if indicated. Decompression of the spinal cord eventually combined with fusion is necessary.

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Year:  2012        PMID: 22370924      PMCID: PMC3369028          DOI: 10.1007/s00586-012-2185-3

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  20 in total

1.  Acute spinal cord compression due to epidural lipomatosis complicated by an abscess: magnetic resonance and pathology findings.

Authors:  Giulio Zuccoli; Nicolò Pipitone; Nicola De Carli; Luigi Vecchia; Stefano C Bartoletti
Journal:  Eur Spine J       Date:  2010-04-06       Impact factor: 3.134

Review 2.  Juvenile idiopathic arthritis.

Authors:  Angelo Ravelli; Alberto Martini
Journal:  Lancet       Date:  2007-03-03       Impact factor: 79.321

3.  Puzzles in practice. Spinal epidural lipomatosis.

Authors:  Yehia Y Mishriki
Journal:  Postgrad Med       Date:  2010-01       Impact factor: 3.840

4.  Case 148: Thoracic epidural lipomatosis.

Authors:  Nanda Venkatanarasimha; Richard W Parrish
Journal:  Radiology       Date:  2009-08       Impact factor: 11.105

5.  Spinal epidural lipomatosis: case reports, literature review and meta-analysis.

Authors:  Guy R Fogel; Paul Y Cunningham; Stephen I Esses
Journal:  Spine J       Date:  2005 Mar-Apr       Impact factor: 4.166

Review 6.  Glomerulonephritis.

Authors:  W G Couser
Journal:  Lancet       Date:  1999-05-01       Impact factor: 79.321

Review 7.  Spinal epidural lipomatosis--a brief review.

Authors:  Darweesh Al-Khawaja; Kevin Seex; Guy D Eslick
Journal:  J Clin Neurosci       Date:  2008-10-26       Impact factor: 1.961

8.  Sudden paraplegia following epidural lipomatosis and thoracal compression fracture after long-term steroid therapy: a case report.

Authors:  Suat Erol Celik; Sait B Erer; Ilker Güleç; Recai Gökcan; Sait Naderi
Journal:  Rheumatol Int       Date:  2009-12-12       Impact factor: 2.631

Review 9.  Chronic obstructive pulmonary disease.

Authors:  J M Madison; R S Irwin
Journal:  Lancet       Date:  1998-08-08       Impact factor: 79.321

Review 10.  COPD exacerbations: defining their cause and prevention.

Authors:  Jadwiga A Wedzicha; Terence A R Seemungal
Journal:  Lancet       Date:  2007-09-01       Impact factor: 79.321

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