Literature DB >> 22369176

Randomized controlled study of a cosmetic treatment for mild acne.

B Capitanio1, J L Sinagra, R B Weller, C Brown, E Berardesca.   

Abstract

BACKGROUND: Cosmetic products are not tested with the same rigour as medical treatments, but recent high-quality studies have shown significant reductions in changes of skin ageing with use of cosmetic antiageing products. AIM: To test whether a cosmetic 'anti-spot' two-step treatment containing a complex of seaweed-derived oligosaccharide and zinc would produce a significant improvement in mild acne.
METHODS: A double-blind, vehicle-controlled trial of this treatment was performed for 8 weeks on 60 age-matched participants with mild acne. They were divided into two groups: 30 participants were treated with vehicle control and 30 with the active treatment containing a seaweed-derived oligosaccharide complexed with 0.1% zinc pyrrolidone.
RESULTS: After 8 weeks, both groups had a reduction in comedones, papules and pustules, and this was significantly greater in the active than control group at 2, 4 and 8 weeks.
CONCLUSIONS: Cosmetic products may offer some benefit for mild acne and still meet the requirements of the European Cosmetic Directive. In particular, the seaweed-derived oligosaccharide complexed with 0.1% zinc pyrrolidone used in this study produced a significant reduction in acne vs. a control treatment. Cosmetic companies should conduct blinded controlled trials of their product's efficacy and publish the results. © The Author(s). CED
© 2012 British Association of Dermatologists.

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Year:  2012        PMID: 22369176     DOI: 10.1111/j.1365-2230.2011.04317.x

Source DB:  PubMed          Journal:  Clin Exp Dermatol        ISSN: 0307-6938            Impact factor:   3.470


  7 in total

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2.  Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.

Authors:  Haibo Liu; Haiyan Yu; Jun Xia; Ling Liu; Guan J Liu; Hong Sang; Frank Peinemann
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Review 3.  Synchronizing Pharmacotherapy in Acne with Review of Clinical Care.

Authors:  Sarvajnamurthy Aradhya Sacchidanand; Koushik Lahiri; Kiran Godse; Narendra Gajanan Patwardhan; Anil Ganjoo; Rajendra Kharkar; Varsha Narayanan; Dhammraj Borade; Lyndon D'souza
Journal:  Indian J Dermatol       Date:  2017 Jul-Aug       Impact factor: 1.494

Review 4.  A review of diagnosis and treatment of acne in adult female patients.

Authors:  A U Tan; B J Schlosser; A S Paller
Journal:  Int J Womens Dermatol       Date:  2017-12-23

5.  External Application of Herbal Medicines for Acne Vulgaris: A Systematic Review and Meta Analysis.

Authors:  Soo-Hyun Sung; Gwang-Ho Choi; Nam-Woo Lee; Byung-Cheul Shin
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6.  Challenges and Solutions in Oral Isotretinoin in Acne: Reflections on 35 Years of Experience.

Authors:  Vincenzo Bettoli; Aurora Guerra-Tapia; Maria Isabel Herane; Jaime Piquero-Martín
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Review 7.  Optimizing Non-Antibiotic Treatments for Patients with Acne: A Review.

Authors:  Theresa N Canavan; Edward Chen; Boni E Elewski
Journal:  Dermatol Ther (Heidelb)       Date:  2016-08-19
  7 in total

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