S Dalbayrak1, M Altas, R Arslan. 1. Dr. Lütfi Kirdar Kartal Research and Training Hospital, First Neurosurgery Clinic, Istanbul, Turkey.
Abstract
OBJECTIVE: The purpose of the present study was to compare the effects of early and late surgery on postoperative vasospasm and mortality in patients with subarachnoid hemorrhage (SAH). METHODS: The data of patients with SAH who underwent aneurysmal clipping at the Kartal Training and Research Hospital between 1999 and 2005 were retrospectively analyzed. The patients who underwent early (0-3 days) and late surgery (> or = 4 days) were evaluated as two groups. Patient outcomes were assessed 1 month after surgery. RESULTS: Of 159 patients (mean age, 49 years; 71 males) with SAHs, 135 (mean age, 51 years; 55 males) underwent early surgery and 24 patients (mean age, 56 years; 16 males) underwent late surgery. The overall postoperative vasospasm rate was 10.7%. The rate of postoperative vasospasm was significantly higher in the late surgery group (41.7%) compared to the early surgery group (5.2%; p < 0.001). There were 15 post-operative deaths (9.4%). The mortality rate in the late surgery group (25.0%) was significantly higher than the early surgery group (6.7%; p = 0.005). CONCLUSIONS: The present study has demonstrated that early surgery is advantageous over late surgery in patients with SAH with lower post-operative vasospasm and mortality rates.
OBJECTIVE: The purpose of the present study was to compare the effects of early and late surgery on postoperative vasospasm and mortality in patients with subarachnoid hemorrhage (SAH). METHODS: The data of patients with SAH who underwent aneurysmal clipping at the Kartal Training and Research Hospital between 1999 and 2005 were retrospectively analyzed. The patients who underwent early (0-3 days) and late surgery (> or = 4 days) were evaluated as two groups. Patient outcomes were assessed 1 month after surgery. RESULTS: Of 159 patients (mean age, 49 years; 71 males) with SAHs, 135 (mean age, 51 years; 55 males) underwent early surgery and 24 patients (mean age, 56 years; 16 males) underwent late surgery. The overall postoperative vasospasm rate was 10.7%. The rate of postoperative vasospasm was significantly higher in the late surgery group (41.7%) compared to the early surgery group (5.2%; p < 0.001). There were 15 post-operative deaths (9.4%). The mortality rate in the late surgery group (25.0%) was significantly higher than the early surgery group (6.7%; p = 0.005). CONCLUSIONS: The present study has demonstrated that early surgery is advantageous over late surgery in patients with SAH with lower post-operative vasospasm and mortality rates.
Authors: Agnes T Stauning; Frank Eriksson; Goetz Benndorf; Anders V Holst; John Hauerberg; Trine Stavngaard; Lars Poulsgaard; Per Rochat; Vagn Eskesen; Peter Birkeland; Tiit Mathiesen; Tina N Munch Journal: Acta Neurochir (Wien) Date: 2022-07-22 Impact factor: 2.816
Authors: Abdolkarim Rahmanian; Mohammad Jamali; Ali Razmkon; Juri Kivelev; Rossana Romani; Ehsan-Ali Alibai; Juha Hernesniemi Journal: Surg Neurol Int Date: 2012-12-26