Literature DB >> 22368263

The effect on quality of life of long-term botulinum toxin A injections to maintain ocular alignment in adult patients with strabismus.

Joanne Hancox1, Shanel Sharma, Kelly MacKenzie, Gill Adams.   

Abstract

BACKGROUND: There is considerable evidence to show that strabismus patients report their quality of life (QoL) as lower than normal controls. While the majority of patients with strabismus are treated with surgery there are a number of cases where surgery is not possible and good long-term ocular alignment can be maintained with repeated injections of botulinum toxin.
METHODS: 65 patients who had undergone over 25 injections of botulinum toxin A for long-term control of their deviation were identified and asked to fill in and return the Adult Strabismus questionnaire (AS-20) to assess their QoL.
RESULTS: 46 questionnaires were available for analysis. The mean AS-20 score in our patients compared favourably with that reported for normal controls and was much higher than that reported for patients with strabismus.
CONCLUSION: Long-term injections with botulinum toxin A is a good treatment for maintaining ocular alignment if squint surgery is not indicated and those patients receiving treatment score near the level of normal controls in QoL terms.

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Year:  2012        PMID: 22368263     DOI: 10.1136/bjophthalmol-2011-301332

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  5 in total

1.  Awareness, perceptions and knowledge of strabismus among patients visiting a tertiary eye clinic in Southwest Nigeria.

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Review 2.  [Use of botulinum toxin in strabismus].

Authors:  B Wabbels
Journal:  Ophthalmologe       Date:  2016-07       Impact factor: 1.059

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Authors:  Iris S Kassem; Marilyn T Miller; Steven M Archer
Journal:  Asia Pac J Ophthalmol (Phila)       Date:  2013 Nov-Dec

Review 4.  Clinical uses of botulinum neurotoxins: current indications, limitations and future developments.

Authors:  Sheng Chen
Journal:  Toxins (Basel)       Date:  2012-10-19       Impact factor: 4.546

5.  Gain beyond cosmesis: demonstration of psychosocial and functional gains following successful strabismus surgery using the adult strabismus questionnaire adult strabismus 20.

Authors:  Danish Alam; Adeeb Alam Khan; Sadat Ao Bani; Richa Sharma; Abadan K Amitava
Journal:  Indian J Ophthalmol       Date:  2014-07       Impact factor: 1.848

  5 in total

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