Literature DB >> 22368248

Unipro UGENE: a unified bioinformatics toolkit.

Konstantin Okonechnikov1, Olga Golosova, Mikhail Fursov.   

Abstract

UNLABELLED: Unipro UGENE is a multiplatform open-source software with the main goal of assisting molecular biologists without much expertise in bioinformatics to manage, analyze and visualize their data. UGENE integrates widely used bioinformatics tools within a common user interface. The toolkit supports multiple biological data formats and allows the retrieval of data from remote data sources. It provides visualization modules for biological objects such as annotated genome sequences, Next Generation Sequencing (NGS) assembly data, multiple sequence alignments, phylogenetic trees and 3D structures. Most of the integrated algorithms are tuned for maximum performance by the usage of multithreading and special processor instructions. UGENE includes a visual environment for creating reusable workflows that can be launched on local resources or in a High Performance Computing (HPC) environment. UGENE is written in C++ using the Qt framework. The built-in plugin system and structured UGENE API make it possible to extend the toolkit with new functionality.
AVAILABILITY AND IMPLEMENTATION: UGENE binaries are freely available for MS Windows, Linux and Mac OS X at http://ugene.unipro.ru/download.html. UGENE code is licensed under the GPLv2; the information about the code licensing and copyright of integrated tools can be found in the LICENSE.3rd_party file provided with the source bundle.

Entities:  

Mesh:

Year:  2012        PMID: 22368248     DOI: 10.1093/bioinformatics/bts091

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  659 in total

1.  Fatty acylation of Wnt proteins.

Authors:  Aaron H Nile; Rami N Hannoush
Journal:  Nat Chem Biol       Date:  2016-02       Impact factor: 15.040

2.  Synteny and comparative analysis of miRNA retention, conservation, and structure across Brassicaceae reveals lineage- and sub-genome-specific changes.

Authors:  Aditi Jain; Sandip Das
Journal:  Funct Integr Genomics       Date:  2016-02-12       Impact factor: 3.410

3.  Pathways associated with lignin biosynthesis in lignomaniac jute fibres.

Authors:  Avrajit Chakraborty; Debabrata Sarkar; Pratik Satya; Pran Gobinda Karmakar; Nagendra Kumar Singh
Journal:  Mol Genet Genomics       Date:  2015-02-28       Impact factor: 3.291

4.  Genomic, Phenotypic, and Virulence Analysis of Streptococcus sanguinis Oral and Infective-Endocarditis Isolates.

Authors:  Shannon P Baker; Tara J Nulton; Todd Kitten
Journal:  Infect Immun       Date:  2018-12-19       Impact factor: 3.441

5.  Acquisition of an Archaea-like ribonuclease H domain by plant L1 retrotransposons supports modular evolution.

Authors:  Georgy Smyshlyaev; Franka Voigt; Alexander Blinov; Orsolya Barabas; Olga Novikova
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-25       Impact factor: 11.205

6.  Genome Mining and Predictive Functional Profiling of Acidophilic Rhizobacterium Pseudomonas fluorescens Pt14.

Authors:  Pooja Rani; Nitish Kumar Mahato; Anukriti Sharma; Desiraju Lakshmi Narsimha Rao; Komal Kamra; Rup Lal
Journal:  Indian J Microbiol       Date:  2017-04-18       Impact factor: 2.461

7.  Lack of methylation in the upstream region of human papillomavirus type 6 from aerodigestive tract papillomas.

Authors:  Agustín Enrique Ure; Ola Forslund
Journal:  J Virol       Date:  2012-10-03       Impact factor: 5.103

8.  Identification and characterization of large-scale genomic rearrangements during wheat evolution.

Authors:  Inbar Bariah; Danielle Keidar-Friedman; Khalil Kashkush
Journal:  PLoS One       Date:  2020-04-14       Impact factor: 3.240

9.  Terminal Olefin Profiles and Phylogenetic Analyses of Olefin Synthases of Diverse Cyanobacterial Species.

Authors:  Tao Zhu; Thibault Scalvenzi; Nathalie Sassoon; Xuefeng Lu; Muriel Gugger
Journal:  Appl Environ Microbiol       Date:  2018-06-18       Impact factor: 4.792

10.  Methyl transfer by substrate signaling from a knotted protein fold.

Authors:  Thomas Christian; Reiko Sakaguchi; Agata P Perlinska; Georges Lahoud; Takuhiro Ito; Erika A Taylor; Shigeyuki Yokoyama; Joanna I Sulkowska; Ya-Ming Hou
Journal:  Nat Struct Mol Biol       Date:  2016-08-29       Impact factor: 15.369

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