Literature DB >> 22365824

The mediator couples transcription and splicing.

Xiong Ji1, Xiang-Dong Fu.   

Abstract

Transcription is coupled with pre-mRNA splicing in metazoans. In the current issue of Molecular Cell, Huang et al. (2012) show that Med23 interacts with the RNA binding protein hnRNP L to regulate alternative splicing, thus expanding Mediator's function beyond transcriptional control. Copyright Â
© 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22365824      PMCID： PMC3292770          DOI： 10.1016/j.molcel.2012.02.003

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  10 in total

Review 1.  Pre-mRNA splicing: where and when in the nucleus.

Authors:  Joonhee Han; Ji Xiong; Dong Wang; Xiang-Dong Fu
Journal:  Trends Cell Biol       Date:  2011-04-21       Impact factor: 20.808

2.  Mediator complex regulates alternative mRNA processing via the MED23 subunit.

Authors:  Yan Huang; Wencheng Li; Xiao Yao; Qi-Jiang Lin; Jing-Wen Yin; Yan Liang; Monika Heiner; Bin Tian; Jingyi Hui; Gang Wang
Journal:  Mol Cell       Date:  2012-01-19       Impact factor: 17.970

3.  Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing.

Authors:  Robert J Sims; Scott Millhouse; Chi-Fu Chen; Brian A Lewis; Hediye Erdjument-Bromage; Paul Tempst; James L Manley; Danny Reinberg
Journal:  Mol Cell       Date:  2007-11-30       Impact factor: 17.970

Review 4.  Functional integration of transcriptional and RNA processing machineries.

Authors:  Shatakshi Pandit; Dong Wang; Xiang-Dong Fu
Journal:  Curr Opin Cell Biol       Date:  2008-04-22       Impact factor: 8.382

Review 5.  Pause locally, splice globally.

Authors:  Fernando Carrillo Oesterreich; Nicole Bieberstein; Karla M Neugebauer
Journal:  Trends Cell Biol       Date:  2011-04-27       Impact factor: 20.808

6.  Functional association between promoter structure and transcript alternative splicing.

Authors:  P Cramer; C G Pesce; F E Baralle; A R Kornblihtt
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-14       Impact factor: 11.205

7.  Human mediator subunit MED26 functions as a docking site for transcription elongation factors.

Authors:  Hidehisa Takahashi; Tari J Parmely; Shigeo Sato; Chieri Tomomori-Sato; Charles A S Banks; Stephanie E Kong; Henrietta Szutorisz; Selene K Swanson; Skylar Martin-Brown; Michael P Washburn; Laurence Florens; Chris W Seidel; Chengqi Lin; Edwin R Smith; Ali Shilatifard; Ronald C Conaway; Joan W Conaway
Journal:  Cell       Date:  2011-07-08       Impact factor: 41.582

Review 8.  The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation.

Authors:  Sohail Malik; Robert G Roeder
Journal:  Nat Rev Genet       Date:  2010-10-13       Impact factor: 53.242

9.  Context-dependent regulatory mechanism of the splicing factor hnRNP L.

Authors:  Laura B Motta-Mena; Florian Heyd; Kristen W Lynch
Journal:  Mol Cell       Date:  2010-01-29       Impact factor: 17.970

10.  HnRNP L stimulates splicing of the eNOS gene by binding to variable-length CA repeats.

Authors:  Jingyi Hui; Karl Stangl; William S Lane; Albrecht Bindereif
Journal:  Nat Struct Biol       Date:  2003-01
  10 in total
  3 in total

Review 1.  Vitamin D and alternative splicing of RNA.

Authors:  Rui Zhou; Rene F Chun; Thomas S Lisse; Alejandro J Garcia; Jianzhong Xu; John S Adams; Martin Hewison
Journal:  J Steroid Biochem Mol Biol       Date:  2014-10-16       Impact factor: 4.292

2.  Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma.

Authors:  Hua Dong; Lan Zhang; Ziliang Qian; Xuehua Zhu; Guanshan Zhu; Yunqin Chen; Xiaoying Xie; Qinghai Ye; Jie Zang; Zhenggang Ren; Qunsheng Ji
Journal:  PLoS One       Date:  2015-04-22       Impact factor: 3.240

3.  The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain.

Authors:  Saikat Bhattacharya; Michaella J Levy; Ning Zhang; Hua Li; Laurence Florens; Michael P Washburn; Jerry L Workman
Journal:  Nat Commun       Date:  2021-03-04       Impact factor: 14.919
  3 in total

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