| Literature DB >> 22365561 |
Zhiqin Ji1, Shaopeng Wei, Lixia Fan, Wenjun Wu.
Abstract
Three novel cyclic hexapeptides, designated NW-G05 (1), NW-G06 (2) and NW-G07 (3), were isolated from the fermentation broth of Streptomyces alboflavus 313. Their structures were elucidated on the basis of extensive spectroscopic analysis, MS experiments, and chemical analysis. Their antibacterial activities against several strains of bacteria were evaluated by micro-broth dilution method. Among these compounds, NW-G06 (2) and NW-G07 (3) displayed highly antibacterial activity against gram-positive bacteria, but not gram negative ones. However, NW-G05 (1) was not active against all tested microorganisms. Copyright ÂEntities:
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Year: 2012 PMID： 22365561 DOI： 10.1016/j.ejmech.2012.02.008
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514