Literature DB >> 22364904

Outcomes of ileocolic resection and right hemicolectomies for Crohn's patients in comparison with non-Crohn's patients and the impact of perioperative immunosuppressive therapy with biologics and steroids on inpatient complications.

Christopher Mascarenhas1, Robert Nunoo, Theodor Asgeirsson, Rachelle Rivera, Don Kim, Rebecca Hoedema, Nadav Dujovny, Martin Luchtefeld, Alan T Davis, Ryan Figg.   

Abstract

BACKGROUND: The purpose of this study was to compare medication use and complication rates between Crohn's disease (CD) and non-CD patients undergoing ileocolic resections and right hemicolectomies.
METHODS: A review of patients who underwent ileocolic resections and right hemicolectomies from January 1, 2003, through December 31, 2010, was performed. Data collected included demographics and clinical information, biologics use (eg, infliximab, adalimumab), other medication use (eg, steroids), complications, and mortality.
RESULTS: There were 791 records reviewed, with 93 CD patients. There was no significant difference in major or minor complications, anastomotic leaks, operating room time, or postoperative ileus occurrence between the CD and non-CD groups (P > .05). Use of biologics and steroids were significantly higher among the CD patients. Mortality, age, and American Society of Anesthesiologists score were significantly higher in the non-CD group.
CONCLUSIONS: Ileocolic resections and right hemicolectomies in CD patients are not associated with an increase in complication rates even when the patients use steroids and biologics in the preoperative period.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22364904     DOI: 10.1016/j.amjsurg.2011.11.001

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  7 in total

Review 1.  Perioperative Considerations in Crohn Disease and Ulcerative Colitis.

Authors:  T Paul Nickerson; Amit Merchea
Journal:  Clin Colon Rectal Surg       Date:  2016-06

2.  Post-operative abdominal complications in Crohn's disease in the biological era: Systematic review and meta-analysis.

Authors:  Peter Waterland; Thanos Athanasiou; Heena Patel
Journal:  World J Gastrointest Surg       Date:  2016-03-27

Review 3.  Inflammatory bowel disease surgery in the biologic era.

Authors:  Linda Ferrari; Mukta K Krane; Alessandro Fichera
Journal:  World J Gastrointest Surg       Date:  2016-05-27

Review 4.  Surgical management of IBD--from an open to a laparoscopic approach.

Authors:  Léon Maggiori; Yves Panis
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2013-02-19       Impact factor: 46.802

Review 5.  [Perioperative handling of immunosuppressive therapy].

Authors:  J Wagner; V Luber; J F Lock; U A Dietz; S Lichthardt; N Matthes; K Krajinovic; C-T Germer; S Knop; A Wiegering
Journal:  Chirurg       Date:  2018-02       Impact factor: 0.955

Review 6.  Preoperative optimization of crohn disease.

Authors:  Amit Sharma; Bertram T Chinn
Journal:  Clin Colon Rectal Surg       Date:  2013-06

Review 7.  Anti-Tumor Necrosis Factor-α Antibody Therapy Management Before and After Intestinal Surgery for Inflammatory Bowel Disease: A CCFA Position Paper.

Authors:  Stefan D Holubar; Jennifer Holder-Murray; Mark Flasar; Mark Lazarev
Journal:  Inflamm Bowel Dis       Date:  2015-11       Impact factor: 5.325

  7 in total

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