Literature DB >> 22364422

Intramolecular oxidative diamination and aminohydroxylation of olefins under metal-free conditions.

Hyun Jin Kim1, Seung Hwan Cho, Sukbok Chang.   

Abstract

A metal-free procedure that is simple to operate and convenient to handle was developed for the facile intramolecular oxidative diamination of olefins using an iodobenzene diacetate oxidant and a halide additive to furnish bisindolines at room temperature. The present reaction is featured by mild conditions, a broad substrate scope, and excellent functional group tolerance. The same protocol was successfully extended to the aminohydroxylation.

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Year:  2012        PMID： 22364422     DOI： 10.1021/ol300166q

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Copper-Catalyzed Alkene Aminoazidation as a Rapid Entry to 1,2-Diamines and Installation of an Azide Reporter onto Azahetereocycles.

Authors:  Kun Shen; Qiu Wang
Journal:  J Am Chem Soc       Date:  2017-09-05       Impact factor: 15.419

2.  Vicinal diamination of alkenes under Rh-catalysis.

Authors:  David E Olson; Justin Y Su; D Allen Roberts; J Du Bois
Journal:  J Am Chem Soc       Date:  2014-09-18       Impact factor: 15.419

3.  Intramolecular Aminolactonization for Synthesis of Furoindolin-2-One.

Authors:  Kazuhiro Higuchi; Kazunori Matsumura; Takafumi Arai; Motoki Ito; Shigeo Sugiyama
Journal:  Molecules       Date:  2021-12-24       Impact factor: 4.411

4.  Enantioselective iodolactonization to prepare ε-lactone rings using hypervalent iodine.

Authors:  Jenna L Payne; Zihang Deng; Andrew L Flach; Jeffrey N Johnston
Journal:  Chem Sci       Date:  2022-06-08       Impact factor: 9.969
  4 in total

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