Literature DB >> 22363159

Delayed diagnosis of scrofuloderma misdiagnosed as a bacterial abscess.

Gun-Wook Kim1, Hyun-Je Park, Hoon-Soo Kim, Su-Han Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Eun-Kyung Sim.   

Abstract

An 82-year-old woman presented with a four-month history of an ulcerative plaque overlying her left neck. This lesion had developed as a subcutaneous nodule, gradually increased in size, and evolved into ulcers. Before visiting our Dermatology clinic, the patient had been diagnosed as having a bacterial abscess, but treatments with antibiotics were unsuccessful. The presence of a purulent discharge and prominent ulceration caused further confusion as bacterial abscess, and radiologic evaluation on computed tomography also led to the possibilities of secondary lesions from an abscess or malignancy. However, the characteristic appearance of her lesion allowed us to discern cutaneous tuberculosis, especially scrofuloderma. Based on clinical examinations, staining for acid-fast bacilli, and positive findings of polymerase chain reaction, a quick diagnosis of scrofuloderma was made. After that, she was treated successfully with anti-tuberculosis therapy and the ulcer healed. Our case highlights the problem of delayed diagnosis of scrofuloderma presenting as a bacterial abscess. In conclusion, having a high index of suspicion is needed to diagnose cutaneous tuberculosis correctly.

Entities:  

Keywords:  Bacterial abscess; Scrofuloderma

Year:  2012        PMID: 22363159      PMCID: PMC3283855          DOI: 10.5021/ad.2012.24.1.70

Source DB:  PubMed          Journal:  Ann Dermatol        ISSN: 1013-9087            Impact factor:   1.444


  10 in total

1.  Cutaneous tuberculosis in children and adolescents: a clinicohistological study.

Authors:  P Vashisht; B Sahoo; N Khurana; B S N Reddy
Journal:  J Eur Acad Dermatol Venereol       Date:  2007-01       Impact factor: 6.166

Review 2.  Cutaneous tuberculosis. Current concepts.

Authors:  V N Sehgal; S A Wagh
Journal:  Int J Dermatol       Date:  1990-05       Impact factor: 2.736

3.  Cutaneous tuberculosis in Blackburn district (U.K.): a 15-year prospective series, 1981-95.

Authors:  V M Yates; L P Ormerod
Journal:  Br J Dermatol       Date:  1997-04       Impact factor: 9.302

4.  How soon does cutaneous tuberculosis respond to treatment? Implications for a therapeutic test of diagnosis.

Authors:  M Ramam; Rashmi Mittal; V Ramesh
Journal:  Int J Dermatol       Date:  2005-02       Impact factor: 2.736

Review 5.  Management of cutaneous tuberculosis.

Authors:  Evangeline B Handog; Teresita G Gabriel; Rosario Trinidad V Pineda
Journal:  Dermatol Ther       Date:  2008 May-Jun       Impact factor: 2.851

6.  Scrofuloderma from the acromioclavicular joint presenting as a chronic ulcer in an immunocompetent host.

Authors:  W P Tan; M B Y Tang; H H Tan
Journal:  Singapore Med J       Date:  2007-09       Impact factor: 1.858

7.  Polymerase chain reaction based detection of Mycobacterium tuberculosis in tissues showing granulomatous inflammation without demonstrable acid-fast bacilli.

Authors:  Pa-Fan Hsiao; Chin-Yuan Tzen; Hsiu-Chin Chen; Hsin-Yi Su
Journal:  Int J Dermatol       Date:  2003-04       Impact factor: 2.736

8.  Tuberculous ulcer of the skin.

Authors:  G Lantos; B K Fisher; M Contreras
Journal:  J Am Acad Dermatol       Date:  1988-12       Impact factor: 11.527

9.  Incidence of cutaneous tuberculosis in patients with organ tuberculosis.

Authors:  Ilknur Kivanç-Altunay; Zerrin Baysal; Tugba Rezan Ekmekçi; Adem Köslü
Journal:  Int J Dermatol       Date:  2003-03       Impact factor: 2.736

Review 10.  Cutaneous tuberculosis: diagnosis and treatment.

Authors:  Joseph Barbagallo; Patricia Tager; Rosemary Ingleton; Ranella J Hirsch; Jeffrey M Weinberg
Journal:  Am J Clin Dermatol       Date:  2002       Impact factor: 7.403

  10 in total
  4 in total

1.  Ungual Tuberculosis: A Unique Clinical Case.

Authors:  Ana Cristina da Silva Sousa; Manuel Sousa; David Tente; Nuno Menezes; Armando Baptista; Rita Guedes
Journal:  Skin Appendage Disord       Date:  2019-09-04

2.  Scorfuloderma of cheek (a cutaneous tuberculosis colliquativa cutis): Case report.

Authors:  Ayoub Sabr; Rachid Aloua; Ouassime Kerdoud; Faiçal Slimani
Journal:  Ann Med Surg (Lond)       Date:  2021-03-26

3.  Chronic osteomyelitis of humerus presenting as scrofuloderma.

Authors:  Susmita Sahu; Satyadarshi Pattnaik; Indrani Mohanty; Moningi Venkata Narasimham; Pritilata Panda
Journal:  Indian J Dermatol       Date:  2013-09       Impact factor: 1.494

Review 4.  Cutaneous tuberculosis: epidemiologic, etiopathogenic and clinical aspects - part I.

Authors:  Josemir Belo Dos Santos; Ana Roberta Figueiredo; Cláudia Elise Ferraz; Márcia Helena de Oliveira; Perla Gomes da Silva; Vanessa Lucília Silveira de Medeiros
Journal:  An Bras Dermatol       Date:  2014 Mar-Apr       Impact factor: 1.896

  4 in total

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