Literature DB >> 22361899

An empirical examination of the management of return of individual research results and incidental findings in genomic biobanks.

Gina Johnson1, Frances Lawrenz, Mao Thao.   

Abstract

PURPOSE: The purpose of this study was to examine and document the management and return of individual research results and incidental findings to research participants among biobanks.
METHODS: A comprehensive Internet search was completed to identify biobanks and collect available documents about biobanks and their procedures and policies regarding the return of results. The Internet search was supplemented by an e-mail request to gather further such documents. A total of 2,366 documents were collected for analysis from a sample of 85 biobanks.
RESULTS: The major finding of this empirical work is that the majority of the biobanks in the sample do not address the return of individual research results and incidental findings in their publicly available documents.
CONCLUSION: The results suggest that there is a need for more discussion and guidance about the most appropriate ways for biobanks to consider the return of individual research results and incidental findings and generate policies and procedures that address this issue.

Entities:  

Mesh:

Year:  2012        PMID: 22361899     DOI: 10.1038/gim.2012.20

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  19 in total

1.  "Forward-Thinking" in U.S. Biobanking.

Authors:  R Jean Cadigan; Teresa P Edwards; Dragana Lassiter; Arlene M Davis; Gail E Henderson
Journal:  Genet Test Mol Biomarkers       Date:  2017-01-24

2.  Pediatric Issues in Return of Results and Incidental Findings: Weighing Autonomy and Best Interests.

Authors:  Ingrid A Holm
Journal:  Genet Test Mol Biomarkers       Date:  2017-01-31

3.  Biobanks in the United States: how to identify an undefined and rapidly evolving population.

Authors:  Gregory J Boyer; Warren Whipple; R Jean Cadigan; Gail E Henderson
Journal:  Biopreserv Biobank       Date:  2012-12       Impact factor: 2.300

4.  Association of Researcher Characteristics with Views on Return of Incidental Findings from Genomic Research.

Authors:  Julia Wynn; Josue Martinez; Jimmy Duong; Yuan Zhang; Jo Phelan; Abby Fyer; Robert Klitzman; Paul S Appelbaum; Wendy K Chung
Journal:  J Genet Couns       Date:  2015-01-17       Impact factor: 2.537

5.  Confidentiality in Biobanking Research: A Comparison of Donor and Nondonor Families' Understanding of Risks.

Authors:  Laura A Siminoff; Maureen Wilson-Genderson; Maghboeba Mosavel; Laura Barker; Jennifer Trgina; Heather M Traino
Journal:  Genet Test Mol Biomarkers       Date:  2017-01-25

6.  Biobank participants' preferences for disclosure of genetic research results: perspectives from the OurGenes, OurHealth, OurCommunity project.

Authors:  Nicole L Allen; Elizabeth W Karlson; Susan Malspeis; Bing Lu; Christine E Seidman; Lisa Soleymani Lehmann
Journal:  Mayo Clin Proc       Date:  2014-06       Impact factor: 7.616

7.  Incidental variants are critical for genomics.

Authors:  Leslie G Biesecker
Journal:  Am J Hum Genet       Date:  2013-05-02       Impact factor: 11.025

8.  Managing incidental findings and research results in genomic research involving biobanks and archived data sets.

Authors:  Susan M Wolf; Brittney N Crock; Brian Van Ness; Frances Lawrenz; Jeffrey P Kahn; Laura M Beskow; Mildred K Cho; Michael F Christman; Robert C Green; Ralph Hall; Judy Illes; Moira Keane; Bartha M Knoppers; Barbara A Koenig; Isaac S Kohane; Bonnie Leroy; Karen J Maschke; William McGeveran; Pilar Ossorio; Lisa S Parker; Gloria M Petersen; Henry S Richardson; Joan A Scott; Sharon F Terry; Benjamin S Wilfond; Wendy A Wolf
Journal:  Genet Med       Date:  2012-04       Impact factor: 8.822

9.  Returning Individual Genetic Research Results to Research Participants: Uptake and Outcomes Among Patients With Breast Cancer.

Authors:  Angela R Bradbury; Linda Patrick-Miller; Brian L Egleston; Kara N Maxwell; Laura DiGiovanni; Jamie Brower; Dominique Fetzer; Jill Bennett Gaieski; Amanda Brandt; Danielle McKenna; Jessica Long; Jacquelyn Powers; Jill E Stopfer; Katherine L Nathanson; Susan M Domchek
Journal:  JCO Precis Oncol       Date:  2018-04-16

10.  The return of individual genomic results to research participants: design and pilot study of Tohoku Medical Megabank Project.

Authors:  Hiroshi Kawame; Akimune Fukushima; Nobuo Fuse; Fuji Nagami; Yoichi Suzuki; Mika Sakurai-Yageta; Jun Yasuda; Yumi Yamaguchi-Kabata; Kengo Kinoshita; Soichi Ogishima; Takako Takai; Shinichi Kuriyama; Atsushi Hozawa; Naoki Nakaya; Tomohiro Nakamura; Naoko Minegishi; Junichi Sugawara; Kichiya Suzuki; Hiroaki Tomita; Akira Uruno; Tomoko Kobayashi; Yayoi Aizawa; Tomoharu Tokutomi; Kayono Yamamoto; Kinuko Ohneda; Shigeo Kure; Yoko Aoki; Hideki Katagiri; Yasushi Ishigaki; Shojiro Sawada; Makoto Sasaki; Masayuki Yamamoto
Journal:  J Hum Genet       Date:  2021-07-08       Impact factor: 3.172

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