Literature DB >> 223615

Inhibitors of the renin-angiotensin system in experimental hypertension, with a note on the measurement of angiotensin I, II and III during infusion of converting-enzyme inhibitor.

J J Morton, J Casals-Stenzel, A F Lever, J A Millar, A J Riegger, M Tree.   

Abstract

1 Prolonged infusion (11 h) of both saralasin and angiotensin-converting enzyme inhibitor (SQ20881) gradually lowered BP in two-kidney hypertensive rats to levels similar to that in normotensive rats infused with dextrose. 2 Saralasin did not lower BP in DOCA-salt hypertensive rats. 3 These observations support the notion that in chronic renal hypertension, angiotensin II may maintain hypertension by a slowly developing action. 4 Plasma angiotensin II in rats infused with SQ20881 was suppressed relative to renin, but was not eliminated. 5 Chromatography of angiotensin II extracts from dogs infused with converting enzyme inhibitor (SQ14,225) showed that the very high levels of angiotensin I achieved after treatment with SQ14,225 can lead to falsely high estimated angiotensin II levels as a result of angiotensin I cross-reacting with the angiotensin II assay.

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Year:  1979        PMID： 223615      PMCID： PMC1429317          DOI： 10.1111/j.1365-2125.1979.tb04695.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  26 in total

1.  A slowly developing pressor response to small concentrations of angiotensin. Its bearing on the pathogenesis of chronic renal hypertension.

Authors:  C J DICKINSON; J R LAWRENCE
Journal:  Lancet       Date:  1963-06-22       Impact factor: 79.321

2.  The pressor role of angiotensin in salt deprivation and renal hypertension in rats.

Authors:  T G Coleman; A C Guyton
Journal:  Clin Sci Mol Med Suppl       Date:  1975-06

3.  Effect of angiotensin-converting enzyme inhibitor (SQ 20881) on the plasma concentration of angiotensin I, angiotensin II, and arginine vasopressin in the dog during hemorrhagic shock.

Authors:  J J Morton; P F Semple; I M Ledingham; B Stuart; M A Tehrani; A R Garcia; G McGarrity
Journal:  Circ Res       Date:  1977-09       Impact factor: 17.367

4.  Intrarenal control of electrolyte excretion by angiotensin II.

Authors:  J E Hall; A C Guyton; N C Trippodo; T E Lohmeier; R E McCaa; A W Cowley
Journal:  Am J Physiol       Date:  1977-06

5.  Estimation of angiotensin II concentration in human plasma by radioimmunoassay. Some applications to physiological and clinical states.

Authors:  G Düsterdieck; G McElwee
Journal:  Eur J Clin Invest       Date:  1971-11       Impact factor: 4.686

6.  Stimulation of renal sodium reabsorption by angiotensin II.

Authors:  M D Johnson; R L Malvin
Journal:  Am J Physiol       Date:  1977-04

7.  Quantification of baroreceptor influence on arterial pressure changes seen in primary angiotension-induced hypertension in dogs.

Authors:  A W Cowley; J W DeClue
Journal:  Circ Res       Date:  1976-12       Impact factor: 17.367

8.  The effects of saralasin, an angiotensin II antagonist, on blood pressure and the renin-angiotensin-aldosterone system in normal and hypertensive subjects.

Authors:  J J Brown; W C Brown; R Fraser; A F Lever; J J Morton; J I Robertson; E A Rosei; P M Trust
Journal:  Aust N Z J Med       Date:  1976-08

9.  The course of arterial pressure and the effect of Sar1-Thr8-angiotensin II in a new model of two-kidney hypertension in conscious dogs.

Authors:  Z Masaki; C M Ferrario; F M Bumpus; E L Bravo; M C Khosla
Journal:  Clin Sci Mol Med       Date:  1977-02

10.  Correction of renal hypertension in the rat by prolonged infusion of angiotensin inhibitors.

Authors:  A J Riegger; A F Lever; J A Millar; J J Morton; B Slack
Journal:  Lancet       Date:  1977 Dec 24-31       Impact factor: 79.321
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  8 in total

Review 1.  Role of angiotensin III in hypertension.

Authors:  Annabelle Reaux-Le Goazigo; Xavier Iturrioz; Celine Fassot; Cedric Claperon; Bernard P Roques; Catherine Llorens-Cortes
Journal:  Curr Hypertens Rep       Date:  2005-04       Impact factor: 5.369

2.  The effect of captopril (SQ14,225) upon mother and fetus in the chronically cannulated ewe and in the pregnant rabbit.

Authors:  F Broughton Pipkin; E M Symonds; S R Turner
Journal:  J Physiol       Date:  1982-02       Impact factor: 5.182

3.  Evidence for participation of kinins in the antihypertensive effect of converting enzyme inhibition.

Authors:  A Overlack; K O Stumpe; M Kühnert; R Kolloch; C Ressel; I Heck; F Krück
Journal:  Klin Wochenschr       Date:  1981-01-15

4.  Brain renin-angiotensin system blockade by systemically active aminopeptidase A inhibitors: a potential treatment of salt-dependent hypertension.

Authors:  Marie-Claude Fournie-Zaluski; Celine Fassot; Bruno Valentin; Dragan Djordjijevic; Annabelle Reaux-Le Goazigo; Pierre Corvol; Bernard P Roques; Catherine Llorens-Cortes
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-10       Impact factor: 11.205

Review 5.  Aminopeptidase A inhibitors as centrally acting antihypertensive agents.

Authors:  Laurence Bodineau; Alain Frugière; Yannick Marc; Cédric Claperon; Catherine Llorens-Cortes
Journal:  Heart Fail Rev       Date:  2008-01-03       Impact factor: 4.214

6.  Prevention of hypertension-induced vascular dementia by Lactobacillus paracasei subsp. paracasei NTU 101-fermented products.

Authors:  Meng-Chun Cheng; Tzu-Ming Pan
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

7.  Focus on Brain Angiotensin III and Aminopeptidase A in the Control of Hypertension.

Authors:  John W Wright; Shigehiko Mizutani; Joseph W Harding
Journal:  Int J Hypertens       Date:  2012-06-26       Impact factor: 2.420

Review 8.  Aminopeptidases in Cardiovascular and Renal Function. Role as Predictive Renal Injury Biomarkers.

Authors:  Félix Vargas; Rosemary Wangesteen; Isabel Rodríguez-Gómez; Joaquín García-Estañ
Journal:  Int J Mol Sci       Date:  2020-08-05       Impact factor: 5.923
  8 in total

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