Literature DB >> 22361444

A detailed association analysis between the tryptophan hydroxylase 2 (TPH2) gene and autism spectrum disorders in a Japanese population.

Jun Egawa1, Yuichiro Watanabe, Ayako Nunokawa, Taro Endo, Naoshi Kaneko, Ryu Tamura, Toshiro Sugiyama, Toshiyuki Someya.   

Abstract

We conducted a detailed association analysis between the tryptophan hydroxylase 2 gene and autism spectrum disorders in a Japanese population using 19 markers, including tagging single nucleotide polymorphisms and a novel missense variation, p.R225Q, identified through exon resequencing. However, we failed to obtain supportive evidence for an association.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID: 22361444     DOI: 10.1016/j.psychres.2011.09.001

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN: 0165-1781            Impact factor:   3.222


  7 in total

Review 1.  Neuroimaging endophenotypes in autism spectrum disorder.

Authors:  Rajneesh Mahajan; Stewart H Mostofsky
Journal:  CNS Spectr       Date:  2015-08       Impact factor: 3.790

Review 2.  Extreme enhancement or depletion of serotonin transporter function and serotonin availability in autism spectrum disorder.

Authors:  Valentina R Garbarino; T Lee Gilman; Lynette C Daws; Georgianna G Gould
Journal:  Pharmacol Res       Date:  2018-07-24       Impact factor: 7.658

3.  Testing genetic modifiers of behavior and response to atomoxetine in autism spectrum disorder with ADHD.

Authors:  Elizabeth S Barrie; Julia K Pinsonneault; Wolfgang Sadee; Jill A Hollway; Benjamin L Handen; Tristram Smith; L Eugene Arnold; Eric Butter; Emily Hansen-Kiss; Gail E Herman; Michael G Aman
Journal:  J Dev Phys Disabil       Date:  2018-03-05

4.  Mice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autism.

Authors:  Michael J Kane; Mariana Angoa-Peréz; Denise I Briggs; Catherine E Sykes; Dina M Francescutti; David R Rosenberg; Donald M Kuhn
Journal:  PLoS One       Date:  2012-11-06       Impact factor: 3.240

5.  Reduced isolation-induced pup ultrasonic communication in mouse pups lacking brain serotonin.

Authors:  Valentina Mosienko; Daniel Beis; Natalia Alenina; Markus Wöhr
Journal:  Mol Autism       Date:  2015-03-08       Impact factor: 7.509

6.  Upregulated NMDAR-mediated GABAergic transmission underlies autistic-like deficits in Htr3a knockout mice.

Authors:  Lang Huang; Jing Wang; Guanmei Liang; Yue Gao; Shi-Yang Jin; Jian Hu; Xiaoxue Yang; Jianpei Lao; Jinfa Chen; Zhou-Cai Luo; Cuixia Fan; Li Xiong; Xinhong Zhu; Tian-Ming Gao; Mei Zhong; Xinping Yang
Journal:  Theranostics       Date:  2021-09-07       Impact factor: 11.556

7.  Associations Between Variations in TPH1 , TPH2 and SLC6A4 Genes and Postpartum Depression: A Study in the Jordanian Population.

Authors:  Of Khabour; Bh Amarneh; Ea Bani Hani; Im Lataifeh
Journal:  Balkan J Med Genet       Date:  2013-06       Impact factor: 0.519

  7 in total

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