Literature DB >> 22358987

Expression of interferon genes in murine macrophages: Possible role of endogenous interferon in the modulation of cell differentiation.

P Di Marzio1, S Gessani, L Conti, P Borghi, F Belardelli.   

Abstract

The expression of interferon (IFN)-β gene was studied in mouse peritoneal macrophages (PM) harvested from normal mice (lps ( n )) or LPS-hyporesponsive mice (lps ( d )). A strong direct correlation between the LPS response of PM and their capacity to expressing basal levels of IFN was found. The results suggest that the constitutive expression of IFN-β gene can play an important role not only in the resistance to viral infection but also in the modulation of cell differentiation.

Entities:  

Year:  1991        PMID： 22358987     DOI： 10.1007/BF00736841

Source DB:  PubMed          Journal:  Cytotechnology        ISSN： 0920-9069            Impact factor:   2.058


  5 in total

1.  Bacterial lipopolysaccharide and gamma interferon induce transcription of beta interferon mRNA and interferon secretion in murine macrophages.

Authors:  S Gessani; F Belardelli; A Pecorelli; P Puddu; C Baglioni
Journal:  J Virol       Date:  1989-06       Impact factor: 5.103

2.  Endogenous interferon production by endotoxin-responsive macrophages provides an autostimulatory differentiation signal.

Authors:  S N Vogel; D Fertsch
Journal:  Infect Immun       Date:  1984-08       Impact factor: 3.441

3.  Correlation between the lipopolysaccharide response of mice and the capacity of mouse peritoneal cells to transfer an antiviral state. Role of endogenous interferon.

Authors:  S Gessani; F Belardelli; P Borghi; D Boraschi; I Gresser
Journal:  J Immunol       Date:  1987-09-15       Impact factor: 5.422

4.  Injection of mice with antibody to interferon renders peritoneal macrophages permissive for vesicular stomatitis virus and encephalomyocarditis virus.

Authors:  F Belardelli; F Vignaux; E Proietti; I Gresser
Journal:  Proc Natl Acad Sci U S A       Date:  1984-01       Impact factor: 11.205

5.  Macrophages from endotoxin-hyporesponsive (Lpsd) C3H/HeJ mice are permissive for vesicular stomatitis virus because of reduced levels of endogenous interferon: possible mechanism for natural resistance to virus infection.

Authors:  S N Vogel; D Fertsch
Journal:  J Virol       Date:  1987-03       Impact factor: 5.103
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.