Literature DB >> 22358438

7q-and loss of a polymorphism for the met oncogene in a patient with myelofibrosis.

G Rege-Cambrin1, A Guerrasio, A Serra, A Alfarano, A Stacchini, P Lusso, G Benetton, M Aglietta, M Bonetto, G Saglio.   

Abstract

The met oncogene is the normal counterpart of a chemically-induced transforming gene. The chromosomal localization of met is 7q21-31. In a patient with myelofibrosis and an interstitial deletion on 7q, we demonstrate that a Taq I polymorphism for the met oncogene is lost in the neoplastic cells, thus indicating that the deletion occuring in the long arm of chromosome 7 involves the met locus.

Entities:  

Year:  1987        PMID： 22358438     DOI： 10.1007/BF00351120

Source DB:  PubMed          Journal:  Cytotechnology        ISSN： 0920-9069            Impact factor:   2.058


  9 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Molecular cloning of a new transforming gene from a chemically transformed human cell line.

Authors:  C S Cooper; M Park; D G Blair; M A Tainsky; K Huebner; C M Croce; G F Vande Woude
Journal:  Nature       Date:  1984 Sep 6-11       Impact factor: 49.962

3.  Combined trisomy 1q and monosomy 7q due to translocation 1;7 in myelodysplastic syndromes.

Authors:  C Mecucci; F Ghione; G Tricot; H Van den Berghe
Journal:  Cancer Genet Cytogenet       Date:  1985-11

4.  The human met oncogene is related to the tyrosine kinase oncogenes.

Authors:  M Dean; M Park; M M Le Beau; T S Robins; M O Diaz; J D Rowley; D G Blair; G F Vande Woude
Journal:  Nature       Date:  1985 Nov 28-Dec 4       Impact factor: 49.962

5.  Evidence for a multistep pathogenesis of chronic myelogenous leukemia.

Authors:  P J Fialkow; P J Martin; V Najfeld; G K Penfold; R J Jacobson; J A Hansen
Journal:  Blood       Date:  1981-07       Impact factor: 22.113

6.  An identical translocation between chromosome 1 and 7 in three patients with myelofibrosis and myeloid metaplasia.

Authors:  J P Geraedts; G J den Ottolander; J E Ploem; O G Muntinghe
Journal:  Br J Haematol       Date:  1980-04       Impact factor: 6.998

7.  Monosomy 7 in granulocytes and monocytes in myelodysplastic syndrome.

Authors:  J Kere; T Ruutu; A de la Chapelle
Journal:  N Engl J Med       Date:  1987-02-26       Impact factor: 91.245

8.  Translocation 1;7 in dyshematopoiesis: possibly induced with a nonrandom geographic distribution.

Authors:  J M Scheres; T W Hustinx; R S Holdrinet; J P Geraedts; A Hagemeijer; M van der Blij-Philipsen
Journal:  Cancer Genet Cytogenet       Date:  1984-08

9.  Incidence of involvement of the B and T lymphocyte lineages in chronic myelogenous leukemia.

Authors:  M Nitta; Y Kato; A Strife; M Wachter; J Fried; A Perez; S Jhanwar; R Duigou-Osterndorf; R S Chaganti; B Clarkson
Journal:  Blood       Date:  1985-11       Impact factor: 22.113
  9 in total

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