Literature DB >> 2235803

Relationship of urinary pH to symptoms of 'cystitis'.

W Brumfitt1, J M Hamilton-Miller, J Cooper, A Raeburn.   

Abstract

The pH of urine samples from patients suffering symptoms suggesting urinary infection (e.g. dysuria, frequency, urgency) was measured while the patients were symptomatic and again when they had become asymptomatic. There was no correlation between the urine pH and the incidence or number of symptoms. No differences were observed between either the distribution or means of urine pH values in symptomatic and asymptomatic patients. There were also no significant differences in either symptomatology or urine pH between patients with significant bacteriuria and those without significant bacteriuria. These results cast doubt upon the traditional (but unproved) belief that alkalinizing the urine helps to reduce symptoms of dysuria and/or frequency, whether or not associated with urinary infection.

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Year:  1990        PMID: 2235803      PMCID: PMC2426891          DOI: 10.1136/pgmj.66.779.727

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  10 in total

1.  ACUTE INFECTIONS OF THE URINARY TRACT AND THE URETHRAL SYNDROME IN GENERAL PRACTICE.

Authors:  D J GALLAGHER; J Z MONTGOMERIE; J D NORTH
Journal:  Br Med J       Date:  1965-03-06

2.  PRESENTATION, DIAGNOSIS, AND TREATMENT OF URINARY-TRACT INFECTIONS IN GENERAL PRACTICE.

Authors:  N C MOND; A PERCIVAL; J D WILLIAMS; W BRUMFITT
Journal:  Lancet       Date:  1965-03-06       Impact factor: 79.321

3.  Effect of ascorbic acid on urine pH in man.

Authors:  M C Nahata; L Shrimp; T Lampman; D C McLeod
Journal:  Am J Hosp Pharm       Date:  1977-11

4.  Pathogenesis of the urethral syndrome in women and its diagnosis in general practice.

Authors:  D Brooks; A Maudar
Journal:  Lancet       Date:  1972-10-28       Impact factor: 79.321

5.  Uncomplicated urinary tract infection in women.

Authors:  C E Mabeck
Journal:  Postgrad Med J       Date:  1971-09       Impact factor: 2.401

6.  Treatment of the acute urethral syndrome.

Authors:  W E Stamm; K Running; M McKevitt; G W Counts; M Turck; K K Holmes
Journal:  N Engl J Med       Date:  1981-04-16       Impact factor: 91.245

7.  A simple scoring system for evaluating symptoms, history and urine dipstick testing in the diagnosis of urinary tract infection.

Authors:  F F Dobbs; D M Fleming
Journal:  J R Coll Gen Pract       Date:  1987-03

8.  Clinical judgment in the diagnosis and management of frequency and dysuria in general practice.

Authors:  T C O'Dowd; J E Smail; R R West
Journal:  Br Med J (Clin Res Ed)       Date:  1984-05-05

9.  Urethral syndrome: a self limiting illness.

Authors:  T C O'Dowd; C D Ribeiro; J Munro; R R West; C H Howells; R H Davis
Journal:  Br Med J (Clin Res Ed)       Date:  1984-05-05

10.  Alkalinisation in the management of cystitis.

Authors:  J B Spooner
Journal:  J Int Med Res       Date:  1984       Impact factor: 1.671

  10 in total
  8 in total

Review 1.  Rapid Growth and Metabolism of Uropathogenic Escherichia coli in Relation to Urine Composition.

Authors:  Larry Reitzer; Philippe Zimmern
Journal:  Clin Microbiol Rev       Date:  2019-10-16       Impact factor: 26.132

2.  A pilot randomized study on use of oral acetazolamide in patients with refractory dysuria.

Authors:  Morteza Hamidi; Seyed Mohammad Kazem Aghamir; Alborz Salavati; Ahmad Masoomi
Journal:  Int Urol Nephrol       Date:  2017-03-13       Impact factor: 2.370

3.  Effect of alkalinisation and increased fluid intake on bacterial phagocytosis and killing in urine.

Authors:  R A Gargan; J M Hamilton-Miller; W Brumfitt
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1993-07       Impact factor: 3.267

4.  Urinary tract infections in healthy women: a revolution in management?

Authors:  Chris Del Mar
Journal:  BMC Fam Pract       Date:  2010-05-26       Impact factor: 2.497

Review 5.  Urinary alkalisation for symptomatic uncomplicated urinary tract infection in women.

Authors:  Dermot B O'Kane; Sameer K Dave; Neel Gore; Farhaan Patel; Tammy C Hoffmann; Jeanne L Trill; Chris B Del Mar
Journal:  Cochrane Database Syst Rev       Date:  2016-04-19

6.  Effects of urine alkalinization with sodium bicarbonate orally on lower urinary tract symptoms in female patients: a pilot study.

Authors:  Mehmet Giray Sönmez; Yunus Emre Göğer; Gökhan Ecer; Ahmet Atıcı; Mehmet Serkan Özkent; Ahmet Öztürk
Journal:  Int Urogynecol J       Date:  2017-10-03       Impact factor: 2.894

Review 7.  Advances in Understanding the Human Urinary Microbiome and Its Potential Role in Urinary Tract Infection.

Authors:  Michael L Neugent; Neha V Hulyalkar; Vivian H Nguyen; Philippe E Zimmern; Nicole J De Nisco
Journal:  mBio       Date:  2020-04-28       Impact factor: 7.867

8.  Innovative Approach for Interstitial Cystitis: Vaginal Pessaries Loaded Diazepam-A Preliminary Study.

Authors:  P Capra; P Perugini; M Bleve; P Pavanetto; G Musitelli; B Rovereto; D Porru
Journal:  J Pharm (Cairo)       Date:  2013-01-20
  8 in total

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