Literature DB >> 22357696

CpG methylation as a tool to characterize cell-free Kaposi sarcoma herpesvirus DNA.

Meir Shamay1, Nicholas Hand, M Victor Lemas, Henry B Koon, Susan E Krown, John Wrangle, Prashant Desai, Juan Carlos Ramos, Richard F Ambinder.   

Abstract

We studied the presence of Kaposi sarcoma herpesvirus sequences in cell-free DNA (cfDNA) isolated from the blood of patients with AIDS-related Kaposi sarcoma (KS) and primary effusion lymphoma (PEL). The use of paramagnetic beads linked to methyl-CpG binding domain protein allowed separation of virion and cell-derived DNA. Only virion DNA was detected in the blood of KS patients, whereas cell-derived DNA was detected in a patient with AIDS-related PEL. The difference in the origins of cfDNA in these settings may in part reflect very different proliferative indices in KS and PEL tumor tissue.

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Year:  2012        PMID: 22357696      PMCID: PMC3295606          DOI: 10.1093/infdis/jis032

Source DB:  PubMed          Journal:  J Infect Dis        ISSN: 0022-1899            Impact factor:   5.226


  15 in total

Review 1.  Update on KSHV epidemiology, Kaposi Sarcoma pathogenesis, and treatment of Kaposi Sarcoma.

Authors:  Thomas S Uldrick; Denise Whitby
Journal:  Cancer Lett       Date:  2011-03-04       Impact factor: 8.679

2.  KSHV: forgotten but not gone.

Authors:  Patrick S Moore; Yuan Chang
Journal:  Blood       Date:  2011-06-30       Impact factor: 22.113

Review 3.  Cell-free nucleic acids as biomarkers in cancer patients.

Authors:  Heidi Schwarzenbach; Dave S B Hoon; Klaus Pantel
Journal:  Nat Rev Cancer       Date:  2011-05-12       Impact factor: 60.716

4.  Over-expression of p45(SKP2) in Kaposi's sarcoma correlates with higher tumor stage and extracutaneous involvement but is not directly related to p27(KIP1) down-regulation.

Authors:  R M Penin; M T Fernandez-Figueras; L Puig; J Rex; C Ferrandiz; A Ariza
Journal:  Mod Pathol       Date:  2002-11       Impact factor: 7.842

5.  Persistence of Kaposi sarcoma-associated herpesvirus (KSHV)-infected cells in KSHV/HIV-1-coinfected subjects without KSHV-associated diseases.

Authors:  Thomas B Campbell; Katherine A Staskus; Joy Folkvord; Irene E White; James Neid; Xing-Quan Zhang; Elizabeth Connick
Journal:  J Infect Dis       Date:  2004-12-23       Impact factor: 5.226

6.  Clonal immunoglobulin DNA in the plasma of patients with AIDS lymphoma.

Authors:  Nina D Wagner-Johnston; Lan Gellert; Christopher D Gocke; Victor M Lemas; Jeannette Lee; Otoniel Martínez-Maza; Richard F Ambinder
Journal:  Blood       Date:  2011-03-09       Impact factor: 22.113

7.  Proliferation in HHV-8-positive primary effusion lymphomas is associated with expression of HHV-8 cyclin but independent of p27(kip1).

Authors:  A Carbone; A Gloghini; D Bontempo; P Monini; U Tirelli; R Volpe; P J Browning; G Gaidano
Journal:  Am J Pathol       Date:  2000-04       Impact factor: 4.307

8.  Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma.

Authors:  Henry B Koon; Barbara Fingleton; Jeannette Y Lee; Julia T Geyer; Ethel Cesarman; Robert A Parise; Merrill J Egorin; Bruce J Dezube; David Aboulafia; Susan E Krown
Journal:  J Acquir Immune Defic Syndr       Date:  2011-01-01       Impact factor: 3.731

9.  The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes.

Authors:  Thomas Günther; Adam Grundhoff
Journal:  PLoS Pathog       Date:  2010-06-03       Impact factor: 6.823

10.  Combination of methylated-DNA precipitation and methylation-sensitive restriction enzymes (COMPARE-MS) for the rapid, sensitive and quantitative detection of DNA methylation.

Authors:  Srinivasan Yegnasubramanian; Xiaohui Lin; Michael C Haffner; Angelo M DeMarzo; William G Nelson
Journal:  Nucleic Acids Res       Date:  2006-02-09       Impact factor: 16.971

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  7 in total

1.  Does Size Matter? Comparison of Extraction Yields for Different-Sized DNA Fragments by Seven Different Routine and Four New Circulating Cell-Free Extraction Methods.

Authors:  Linda Cook; Kimberly Starr; Jerry Boonyaratanakornkit; Randall Hayden; Soya S Sam; Angela M Caliendo
Journal:  J Clin Microbiol       Date:  2018-11-27       Impact factor: 5.948

Review 2.  Tracking myeloma tumor DNA in peripheral blood.

Authors:  Johannes M Waldschmidt; Tushara Vijaykumar; Birgit Knoechel; Jens G Lohr
Journal:  Best Pract Res Clin Haematol       Date:  2020-01-14       Impact factor: 3.020

Review 3.  Diagnosis and management of lymphomas and other cancers in HIV-infected patients.

Authors:  Antonino Carbone; Emanuela Vaccher; Annunziata Gloghini; Liron Pantanowitz; Akin Abayomi; Paolo de Paoli; Silvia Franceschi
Journal:  Nat Rev Clin Oncol       Date:  2014-03-11       Impact factor: 66.675

4.  Modulation of Cellular CpG DNA Methylation by Kaposi's Sarcoma-Associated Herpesvirus.

Authors:  Guy Journo; Carmel Tushinsky; Asia Shterngas; Nir Avital; Yonatan Eran; Marcela Viviana Karpuj; Milana Frenkel-Morgenstern; Meir Shamay
Journal:  J Virol       Date:  2018-07-31       Impact factor: 5.103

5.  γ-Herpesvirus load as surrogate marker of early death in HIV-1 lymphoma patients submitted to high dose chemotherapy and autologous peripheral blood stem cell transplantation.

Authors:  Chiara Pratesi; Stefania Zanussi; Rosamaria Tedeschi; Maria Teresa Bortolin; Renato Talamini; Maurizio Rupolo; Chiara Scaini; Giancarlo Basaglia; Matteo Di Maso; Mario Mazzucato; Ernesto Zanet; Umberto Tirelli; Mariagrazia Michieli; Antonino Carbone; Paolo De Paoli
Journal:  PLoS One       Date:  2015-02-10       Impact factor: 3.240

6.  Kaposi's sarcoma-associated herpesvirus genome programming during the early stages of primary infection of peripheral blood mononuclear cells.

Authors:  Hem C Jha; Jie Lu; Subhash C Verma; Shuvomoy Banerjee; Devan Mehta; Erle S Robertson
Journal:  mBio       Date:  2014-12-16       Impact factor: 7.867

7.  High-throughput sequencing analysis of a "hit and run" cell and animal model of KSHV tumorigenesis.

Authors:  Julian Naipauer; Daria Salyakina; Guy Journo; Santas Rosario; Sion Williams; Martin Abba; Meir Shamay; Enrique A Mesri
Journal:  PLoS Pathog       Date:  2020-06-30       Impact factor: 6.823

  7 in total

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