Literature DB >> 22357097

Incidence, risk factors, and natural course of proximal junctional kyphosis: surgical outcomes review of adult idiopathic scoliosis. Minimum 5 years of follow-up.

Mitsuru Yagi1, Akilah B King, Oheneba Boachie-Adjei.   

Abstract

STUDY
DESIGN: A retrospective case series of surgically treated patients with adult scoliosis.
OBJECTIVE: The purpose of this study was to evaluate the incidence, risk factors, and natural course of proximal junctional kyphosis (PJK) in a long-term follow-up of patients with adult idiopathic scoliosis undergoing long instrumented spinal fusion. SUMMARY OF BACKGROUND DATA: Although recent reports have showed the prevalence, clinical outcomes, and the possible risk factors of PJK, quite a few reports have showed long-term follow-up outcome.
MATERIALS AND METHODS: This is a retrospective review of the charts and radiographs of 76 consecutive patients with adult scoliosis treated with long instrumented spinal fusion. Radiographical measurements and demographic data were reviewed on preoperation, immediate postoperation, 2 years postoperation, 5 years postoperation, and at follow-up. Postoperative Scoliosis Research Society scores and Oswestry Disability Index were also evaluated. Means were compared with Student t test. A P value of less than 0.05 with 95% confidence interval was considered significant.
RESULTS: The mean age was 48.8 years (range, 23-75 yr) and the average follow-up was 7.3 years (range, 5-14 yr). PJK has been identified in 17 patients. The Scoliosis Research Society and Oswestry Disability Index did not demonstrate significant differences between PJK group and non-PJK group; 2 patients had additional surgeries performed for local pain. Seventy-six percent of PJK has been identified within 3 months after surgery. Despite the fact that 53% of total degree of PJK was progressed within 3 months after surgery, PJK continuously progressed to the final follow-up. Pre-existing low bone mineral density, posterior spinal fusion (PSF), fusion to sacrum, inappropriate global spine alignment, and greater sagittal vertical axis change were identified as significant risk factors for PJK (P = 0.04, P < 0.001, P = 0.02, P < 0.0001, and P = 0.01).
CONCLUSION: In a long-term review of minimum 5 years, 76% of PJK occurred within 3 months after surgery. Pre-existing low bone mineral density, PSF, fusion to the sacrum, inappropriate global spine alignment, and greater sagittal vertical axis change were significant risk factors for PJK. Careful long-term follow-up should be done for a patient with PJK.

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Year:  2012        PMID: 22357097     DOI: 10.1097/BRS.0b013e31824e4888

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  60 in total

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2.  Walking sagittal balance correction by pedicle subtraction osteotomy in adults with fixed sagittal imbalance.

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3.  Reoperation rates in minimally invasive, hybrid and open surgical treatment for adult spinal deformity with minimum 2-year follow-up.

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5.  Skipping Pedicle Screw Insertion Into Infected Vertebra is a Risk Factor for Revision Surgery for Pyogenic Spondylitis in the Lower Thoracic and Lumbar Spine.

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Review 6.  Proximal junctional kyphosis following adult spinal deformity surgery.

Authors:  Samuel K Cho; John I Shin; Yongjung J Kim
Journal:  Eur Spine J       Date:  2014-09-04       Impact factor: 3.134

Review 7.  Incidence and risk factors of proximal junctional kyphosis after internal fixation for adult spinal deformity: a systematic evaluation and meta-analysis.

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Journal:  Neurosurg Rev       Date:  2020-05-19       Impact factor: 3.042

8.  The mechanism in junctional failure of thoraco-lumbar fusions. Part I: Biomechanical analysis of mechanisms responsible of vertebral overstress and description of the cervical inclination angle (CIA).

Authors:  Jean-Charles Le Huec; Jonathon Richards; Andreas Tsoupras; Rachel Price; Amélie Léglise; Antonio A Faundez
Journal:  Eur Spine J       Date:  2017-12-14       Impact factor: 3.134

9.  Degenerative lumbar scoliosis patients with proximal junctional kyphosis have lower muscularity, fatty degeneration at the lumbar area.

Authors:  Lei Yuan; Yan Zeng; Zhongqiang Chen; Weishi Li; Xinling Zhang; Shuo Mai
Journal:  Eur Spine J       Date:  2020-11-19       Impact factor: 3.134

10.  Teriparatide improves volumetric bone mineral density and fine bone structure in the UIV+1 vertebra, and reduces bone failure type PJK after surgery for adult spinal deformity.

Authors:  M Yagi; H Ohne; T Konomi; K Fujiyoshi; S Kaneko; T Komiyama; M Takemitsu; Y Yato; M Machida; T Asazuma
Journal:  Osteoporos Int       Date:  2016-06-24       Impact factor: 4.507

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