Literature DB >> 22356736

Cyclic dipeptides exhibit potency for scavenging radicals.

Tadashi Furukawa1, Takashi Akutagawa, Hitomi Funatani, Toshikazu Uchida, Yoshihiro Hotta, Masatake Niwa, Yoshiaki Takaya.   

Abstract

Twenty kinds of cyclic dipeptides containing l-leucine were synthesized, and their antioxidant activity against ·OH and O(2)(·-) was investigated. Compounds possessing polar amino acid residues, such as Asp, Cys, Glu, Lys, Pro, Ser, and Trp, exhibited higher antioxidant activity against ·OH than vitamin E. However, only cyclo(l-Cys-l-Leu) scavenged O(2)(·-). Copyright Â
© 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22356736     DOI： 10.1016/j.bmc.2012.01.050

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  8 in total

1.  Cytotoxicity of cyclodipeptides from Pseudomonas aeruginosa PAO1 leads to apoptosis in human cancer cell lines.

Authors:  Dolores Vázquez-Rivera; Omar González; Jaquelina Guzmán-Rodríguez; Alma L Díaz-Pérez; Alejandra Ochoa-Zarzosa; José López-Bucio; Víctor Meza-Carmen; Jesús Campos-García
Journal:  Biomed Res Int       Date:  2015-03-02       Impact factor: 3.411

2.  The Antiproliferative Effect of Cyclodipeptides from Pseudomonas aeruginosa PAO1 on HeLa Cells Involves Inhibition of Phosphorylation of Akt and S6k Kinases.

Authors:  Laura Hernández-Padilla; Dolores Vázquez-Rivera; Luis A Sánchez-Briones; Alma L Díaz-Pérez; José Moreno-Rodríguez; Mario A Moreno-Eutimio; Victor Meza-Carmen; Homero Reyes-De la Cruz; Jesús Campos-García
Journal:  Molecules       Date:  2017-06-20       Impact factor: 4.411

3.  Cyclo-(l-Phe-l-Pro), a Quorum-Sensing Signal of Vibrio vulnificus, Induces Expression of Hydroperoxidase through a ToxR-LeuO-HU-RpoS Signaling Pathway To Confer Resistance against Oxidative Stress.

Authors:  In Hwang Kim; So-Yeon Kim; Na-Young Park; Yancheng Wen; Keun-Woo Lee; So-Young Yoon; Haneul Jie; Kyu-Ho Lee; Kun-Soo Kim
Journal:  Infect Immun       Date:  2018-08-22       Impact factor: 3.441

4.  A Simple Defined Medium for the Production of True Diketopiperazines in Xylella fastidiosa and Their Identification by Ultra-Fast Liquid Chromatography-Electrospray Ionization Ion Trap Mass Spectrometry.

Authors:  Michelli Massaroli da Silva; Moacir Dos Santos Andrade; Anelize Bauermeister; Marcus Vinícius Merfa; Moacir Rossi Forim; João Batista Fernandes; Paulo Cezar Vieira; Maria Fátima das Graças Fernandes da Silva; Norberto Peporine Lopes; Marcos Antônio Machado; Alessandra Alves de Souza
Journal:  Molecules       Date:  2017-06-13       Impact factor: 4.411

5.  High-tolerance crystalline hydrogels formed from self-assembling cyclic dipeptide.

Authors:  Yongcai You; Ruirui Xing; Qianli Zou; Feng Shi; Xuehai Yan
Journal:  Beilstein J Nanotechnol       Date:  2019-09-18       Impact factor: 3.649

Review 6.  Research Progress of the Biosynthesis of Natural Bio-Antibacterial Agent Pulcherriminic Acid in Bacillus.

Authors:  Siqi Yuan; Xihao Yong; Ting Zhao; Yuan Li; Jun Liu
Journal:  Molecules       Date:  2020-11-28       Impact factor: 4.411

7.  Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix Adenocarcinoma.

Authors:  Pedro E Lázaro-Mixteco; José M González-Coronel; Laura Hernández-Padilla; Lorena Martínez-Alcantar; Enrique Martínez-Carranza; Jesús Salvador López-Bucio; Ángel A Guevara-García; Jesús Campos-García
Journal:  Front Oncol       Date:  2022-03-14       Impact factor: 6.244

Review 8.  Cyclodipeptides: An Overview of Their Biosynthesis and Biological Activity.

Authors:  Awdhesh Kumar Mishra; Jaehyuk Choi; Seong-Jin Choi; Kwang-Hyun Baek
Journal:  Molecules       Date:  2017-10-23       Impact factor: 4.411
  8 in total

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