Literature DB >> 22356680

A general preparation of protected phosphoamino acids.

Daniel E Petrillo1, Dale R Mowrey, Shawn P Allwein, Roger P Bakale.   

Abstract

Fmoc-O-benzyl-l-phosphoserine is an important building block in the synthesis of Forigerimod, a phosphopeptide being investigated for Systemic Lupus Erythematosus (SLE). An efficient one-pot process was developed using inexpensive, readily available starting materials. This general procedure was used to prepare a variety of protected phosphoamino acids.
© 2012 American Chemical Society

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Year:  2012        PMID: 22356680     DOI: 10.1021/ol203332j

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  5 in total

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