Literature DB >> 2235667

[Extrapyramidal syndrome caused by moderate overdosage of domperidone. Description of a case].

M Pellegrino1, M Sacco, F Lotti.   

Abstract

Domperidone is useful in the treatment of vomiting and gastroesophageal reflux in children. Its efficaciousness is due to the antagonist effect on gastrointestinal dopaminergic receptors. Contrary to the initial expectations, domperidone is able to penetrate into the hematoencephalic barrier and to cause adverse neurologic reactions. We report a case of extrapyramidal reaction in a child after moderate overdosage of domperidone.

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Year:  1990        PMID: 2235667

Source DB:  PubMed          Journal:  Pediatr Med Chir        ISSN: 0391-5387


  2 in total

1.  Domperidone-induced dystonia: a rare and troublesome complication.

Authors:  Om Prakash Dhakal; Mona Dhakal; Dhurba Bhandari
Journal:  BMJ Case Rep       Date:  2014-06-27

2.  Clinical Spectrum of Drug-Induced Movement Disorders: A Study of 97 Patients.

Authors:  Anjali Chouksey; Sanjay Pandey
Journal:  Tremor Other Hyperkinet Mov (N Y)       Date:  2020-10-26
  2 in total

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