| Literature DB >> 2235667 |
M Pellegrino1, M Sacco, F Lotti.
Abstract
Domperidone is useful in the treatment of vomiting and gastroesophageal reflux in children. Its efficaciousness is due to the antagonist effect on gastrointestinal dopaminergic receptors. Contrary to the initial expectations, domperidone is able to penetrate into the hematoencephalic barrier and to cause adverse neurologic reactions. We report a case of extrapyramidal reaction in a child after moderate overdosage of domperidone.Entities:
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Year: 1990 PMID: 2235667
Source DB: PubMed Journal: Pediatr Med Chir ISSN: 0391-5387