OBJECTIVE: To evaluate the correlation of portal vein thrombosis and splenectomy in beta-thalassemia major patients visiting Babol Medical University, Iran. METHODS: This cohort study was done from 1997 to 2008. In our study, major beta-thalassemic patients visiting for transfusion at least once a month at Amirkola Children's Hospital were selected. Portal vein thrombosis was diagnosed through Doppler ultrasound in symptomatic patients. Cases were 160 beta-thalassemia major patients who underwent splenectomy and 160 remaining thalassemic patients without splenectomy were controls. Statistical comparison with Fisher exact test was performed. RESULTS: Five cases had suffered from portal vein thrombosis (P = 0.03). Majority patients with portal vein thrombosis had their symptoms after first month of the operation. CONCLUSION: Correlation of splenectomy with portal vein thrombosis is statistically significant among beta-thalassemic children from Iran.
OBJECTIVE: To evaluate the correlation of portal vein thrombosis and splenectomy in beta-thalassemia major patients visiting Babol Medical University, Iran. METHODS: This cohort study was done from 1997 to 2008. In our study, major beta-thalassemicpatients visiting for transfusion at least once a month at Amirkola Children's Hospital were selected. Portal vein thrombosis was diagnosed through Doppler ultrasound in symptomatic patients. Cases were 160 beta-thalassemia major patients who underwent splenectomy and 160 remaining thalassemicpatients without splenectomy were controls. Statistical comparison with Fisher exact test was performed. RESULTS: Five cases had suffered from portal vein thrombosis (P = 0.03). Majority patients with portal vein thrombosis had their symptoms after first month of the operation. CONCLUSION: Correlation of splenectomy with portal vein thrombosis is statistically significant among beta-thalassemicchildren from Iran.
Authors: Rafiye Ciftciler; Aysel Pasayeva; Salih Aksu; Osman Ozcebe; Nilgun Sayınalp; Umit Yavuz Malkan; Yahya Buyukasık; Ibrahim C Haznedaroglu Journal: Open Med (Wars) Date: 2019-06-17