Literature DB >> 22354327

Properties of xyloglucan hydrogel as the biomedical sustained-release carriers.

Didi Chen1, Pei Guo, Sha Chen, Yu Cao, Wanzhen Ji, Xia Lei, Lina Liu, Peiguang Zhao, Ruihong Wang, Chao Qi, Yanli Liu, Hongxuan He.   

Abstract

This study introduces an easy method of preparing xyloglucan hydrogel from xyloglucan, which is purified from tamarind seed gum. Xyloglucan hydrogel was prepared in 2 wt% solution by treating with β-galactosidase. Physical and chemical properties (molecular mass, size and viscosity) of xyloglucan hydrogel and xyloglucan solution were tested for a comparison. Experiments of drug release in vitro and in vivo were operated to investigate the potentialities of xyloglucan hydrogel as the biomedical sustained-release carriers for drug delivery system.

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Year:  2012        PMID: 22354327     DOI: 10.1007/s10856-012-4564-z

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN: 0957-4530            Impact factor:   3.896


  14 in total

1.  Thermally reversible xyloglucan gels as vehicles for oral drug delivery.

Authors:  N Kawasaki; R Ohkura; S Miyazaki; Y Uno; S Sugimoto; D Attwood
Journal:  Int J Pharm       Date:  1999-04-30       Impact factor: 5.875

2.  In vitro release of insulin and biocompatibility of in situ forming gel systems.

Authors:  Feirong Kang; Jagdish Singh
Journal:  Int J Pharm       Date:  2005-09-21       Impact factor: 5.875

Review 3.  Drug delivery strategies using polysaccharidic gels.

Authors:  Tommasina Coviello; Pietro Matricardi; Franco Alhaique
Journal:  Expert Opin Drug Deliv       Date:  2006-05       Impact factor: 6.648

4.  Intracellular delivery of mitomycin C with targeted polysaccharide conjugates against multidrug resistance.

Authors:  Yu Cao; Didi Chen; Peiguang Zhao; Lina Liu; Xueying Huang; Chao Qi; Yanli Liu; Hongxuan He; Qian Wang; Yang Liu; Sha Chen
Journal:  Ann Biomed Eng       Date:  2011-06-24       Impact factor: 3.934

Review 5.  Polysaccharide hydrogels for modified release formulations.

Authors:  Tommasina Coviello; Pietro Matricardi; Carlotta Marianecci; Franco Alhaique
Journal:  J Control Release       Date:  2007-01-19       Impact factor: 9.776

6.  Xyloglucan as a synthetic extracellular matrix for hepatocyte attachment.

Authors:  Seog-Jin Seo; In-Kyu Park; Mi-Kyoung Yoo; Mayumi Shirakawa; Toshihiro Akaike; Chong-Su Cho
Journal:  J Biomater Sci Polym Ed       Date:  2004       Impact factor: 3.517

7.  Oral sustained delivery of paracetamol from in situ gelling xyloglucan formulations.

Authors:  Shozo Miyazaki; Kumiko Endo; Naoko Kawasaki; Wataru Kubo; Hideki Watanabe; David Attwood
Journal:  Drug Dev Ind Pharm       Date:  2003-02       Impact factor: 3.225

8.  Self-assembled nanoparticle drug delivery systems from galactosylated polysaccharide-doxorubicin conjugate loaded doxorubicin.

Authors:  Yu Cao; Ying Gu; Hong Ma; Jing Bai; Lina Liu; Peiguang Zhao; Hongxuan He
Journal:  Int J Biol Macromol       Date:  2009-12-01       Impact factor: 6.953

9.  Antitumor effect of pluronic F-127 gel containing mitomycin C on sarcoma-180 ascites tumor in mice.

Authors:  S Miyazaki; Y Ohkawa; M Takada; D Attwood
Journal:  Chem Pharm Bull (Tokyo)       Date:  1992-08       Impact factor: 1.645

10.  Percutaneous absorption of indomethacin from pluronic F127 gels in rats.

Authors:  S Miyazaki; T Tobiyama; M Takada; D Attwood
Journal:  J Pharm Pharmacol       Date:  1995-06       Impact factor: 3.765

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  2 in total

1.  Tamarind Seed Xyloglucans Promote Proliferation and Migration of Human Skin Cells through Internalization via Stimulation of Proproliferative Signal Transduction Pathways.

Authors:  W Nie; A M Deters
Journal:  Dermatol Res Pract       Date:  2013-09-09

2.  Development of a Mucoadhesive in Situ Gelling Formulation for the Delivery of Lactobacillus gasseri into Vaginal Cavity.

Authors:  Barbara Vigani; Angela Faccendini; Silvia Rossi; Giuseppina Sandri; Maria Cristina Bonferoni; Pietro Grisoli; Franca Ferrari
Journal:  Pharmaceutics       Date:  2019-10-03       Impact factor: 6.321

  2 in total

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