| Literature DB >> 22354295 |
Christian G Giske1, Inga Fröding, Chowdhury Mehedi Hasan, Agata Turlej-Rogacka, Mark Toleman, David Livermore, Neil Woodford, Timothy R Walsh.
Abstract
Clinical isolates of Klebsiella pneumoniae producing NDM-1 carbapenemase from India (n = 22), the United Kingdom (n = 13), and Sweden (n = 4) were subjected to multilocus sequence typing (MLST), automated repetitive sequence-based PCR (rep-PCR), serotyping, virulence gene screening, and plasmid replicon typing. The most frequently detected MLST sequence types (STs) were ST14 (n = 13; all serotype K2), ST11, ST149, ST231, and ST147. The correlation between MLST and automated rep-PCR was excellent. IncA/C was the most frequently detected plasmid replicon type (n = 14). ST14, ST11, and other successful clones may be important for the dissemination of bla(NDM-1).Entities:
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Year: 2012 PMID: 22354295 PMCID: PMC3346639 DOI: 10.1128/AAC.06142-11
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191