PURPOSE: To determine the relapse rate within one year for a cohort of children treated for severe early childhood caries (S-ECC). METHODS: In an earlier report, we assessed the suppressive effect of 10 percent povidone-iodine and the elimination of active caries on salivary mutans streptococci (MS) populations in 77 children with S-ECC; 49 children returned for a 6-month recall exam that occurred 5 to 12 months post dental surgery. Relapse declaration required at least one caries lesion needing a restoration. Contrasts of relapse (R) and non-relapse (NR) to the covariates of gender, race, ethnicity, age, surfaces available for relapse (SAR), time to appointment, and baseline salivary mutans streptococci (MS) counts were statistically evaluated. RESULTS: 19 children (39%) were declared R and 30 (61%) were NR. The 2 groups did not statistically differ on: gender, race, ethnicity, age, SAR, baseline salivary MS counts and time to recall appointment. Statistical analyses also showed the covariates had no significant effect on probability of relapse or time to relapse (P>0.05). CONCLUSIONS: None of the covariates were related to R. The R rate (39%) observed is consistent with earlier reports. Novel approaches are needed to improve relapse prevention.
PURPOSE: To determine the relapse rate within one year for a cohort of children treated for severe early childhood caries (S-ECC). METHODS: In an earlier report, we assessed the suppressive effect of 10 percent povidone-iodine and the elimination of active caries on salivary mutans streptococci (MS) populations in 77 children with S-ECC; 49 children returned for a 6-month recall exam that occurred 5 to 12 months post dental surgery. Relapse declaration required at least one caries lesion needing a restoration. Contrasts of relapse (R) and non-relapse (NR) to the covariates of gender, race, ethnicity, age, surfaces available for relapse (SAR), time to appointment, and baseline salivary mutans streptococci (MS) counts were statistically evaluated. RESULTS: 19 children (39%) were declared R and 30 (61%) were NR. The 2 groups did not statistically differ on: gender, race, ethnicity, age, SAR, baseline salivary MS counts and time to recall appointment. Statistical analyses also showed the covariates had no significant effect on probability of relapse or time to relapse (P>0.05). CONCLUSIONS: None of the covariates were related to R. The R rate (39%) observed is consistent with earlier reports. Novel approaches are needed to improve relapse prevention.
Authors: Jin Xiao; Naemah Alkhers; Dorota T Kopycka-Kedzierawski; Ronald J Billings; Tong Tong Wu; Daniel A Castillo; Linda Rasubala; Hans Malmstrom; Yanfang Ren; Eli Eliav Journal: Caries Res Date: 2019-01-10 Impact factor: 4.056
Authors: J Xiao; A Grier; R C Faustoferri; S Alzoubi; A L Gill; C Feng; Y Liu; R G Quivey; D T Kopycka-Kedzierawski; H Koo; S R Gill Journal: J Dent Res Date: 2018-07-26 Impact factor: 6.116
Authors: Karolina Gerreth; Timucin Ari; Wojciech Bednarz; Michal Nowicki; Maria Borysewicz-Lewicka Journal: Med Princ Pract Date: 2019-09-16 Impact factor: 1.927